GSM1503710[Accession] - GEO DataSets

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Items: 4

Select item 2000613921.

MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13112
28 Samples

Download data: BW

Series

Accession:: GSE61392

ID:: 200061392

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Select item 2000613912.

MEF2D drives photoreceptor development through a genome-wide competition for tissue-specific enhancers (ChIP-Seq)

(Submitter supplied) Organismal development requires the precise coordination of genetic programs to regulate cell fate and function. MEF2 transcription factors play essential roles in this process but how these broadly expressed factors contribute to the generation of specific cell types during development is poorly understood. Here we show that despite being expressed in virtually all mammalian tissues, in the retina MEF2D binds to retina-specific enhancers and controls photoreceptor cell development. more...