GSM1398923[Accession] - GEO DataSets

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Items: 3

Select item 2000579701.

Disease severity is associated with differential gene expression at the early and late phases of infection in non-human primates infected with different H5N1 highly pathogenic avian influenza viruses

(Submitter supplied) Occasional transmission of highly pathogenic avian H5N1 influenza viruses to humans causes severe pneumonia with high mortality. To better understand the mechanisms via which H5N1 viruses induce severe disease in humans, we infected cynomolgus macaques with six different H5N1 strains isolated from human patients and compared their pathogenicity and the global host responses to the virus infection. Although all H5N1 viruses replicated in the respiratory tract, there was substantial heterogeneity in their replicative ability and in the disease severity induced, which ranged from asymptomatic to fatal. more...

Organism:: Macaca mulatta

Type:: Expression profiling by array

Platform:: GPL14569
45 Samples

Download data: TXT

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Accession:: GSE57970

ID:: 200057970

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000145692.

Agilent-015421 Rhesus Macaque Gene Expression Microarray (Probe Name Version)

(Submitter supplied) M. mulatta (Rhesus) Oligo Microarray 4x44K Arrays of this design have barcodes that begin with 16015421 or 2515421. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...