GSM1355155[Accession] - GEO DataSets

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Items: 4

Select item 2000561381.

Reorganization of enhancer patterns in transition from naïve to primed pluripotency

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL11002
42 Samples

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Series

Accession:: GSE56138

ID:: 200056138

PubMed Full text in PMC Similar studies

Select item 2000560982.

Reorganization of enhancer patterns in transition from naïve to primed pluripotency (ChIP-seq)

(Submitter supplied) Naïve and primed pluripotency is characterized by distinct signaling requirements, transcriptomes and developmental properties, but both cellular states share key transcriptional regulators, Oct4, Sox2 and Nanog. Here we demonstrate that transition between these two pluripotent states is associated with widespread Oct4 relocalization, mirrored by global rearrangement of enhancer chromatin landscapes. more...