GSM1267914[Accession] - GEO DataSets

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Items: 4

Select item 2000524991.

A crucial role of the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL13912 GPL11002
18 Samples

Download data: TXT, WIG

Series

Accession:: GSE52499

ID:: 200052499

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000524962.

A crucial role of the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification [ChIP-Seq]

(Submitter supplied) Mammalian development is regulated by the interplay of tissue-specific and ubiquitously expressed transcription factors, such as Sp1. Sp1 knock-out mice die in utero with multiple phenotypic aberrations, but the underlying molecular mechanism of this differentiation failure has been elusive. Here we used conditional knock-out mice as well as the differentiation of mouse ES cells as a model to address this issue. more...