GSM1022283[Accession] - GEO DataSets

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Items: 4

Select item 2000383791.

Latent enhancers unveiled by stimulation expand and adapt the available cis-regulatory repertoire

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL9250 GPL13112
124 Samples

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Series

Accession:: GSE38379

ID:: 200038379

PubMed Similar studies

Select item 2000383772.

Latent enhancers unveiled by stimulation expand and adapt the available cis-regulatory repertoire (ChIP-seq)

(Submitter supplied) According to current models, transcription factors (TFs) activated by extracellular stimuli operate in the context of a pre-established enhancer repertoire induced and maintained by lineage-specific TFs. Here, we uncovered the existence of latent enhancers, defined as regions of the genome that in terminally differentiated cells are poorly accessible and lack the histone marks characteristic of enhancers, but readily acquire these features in response to extracellular cues. more...