GEO DataSets

(Submitter supplied) Most mammalian genes produce multiple distinct mRNAs through alternative splicing, but the extent of splicing conservation is not clear.  To assess tissue-specific transcriptome variation across mammals, we sequenced cDNA from 9 tissues from 4 mammals and one bird in biological triplicate, at unprecedented depth.  We find that while tissue-specific gene expression programs are largely conserved, alternative splicing is well conserved in only a subset of tissues and is frequently lineage-specific. more...

Organism:

Gallus gallus; Bos taurus; Mus musculus; Rattus norvegicus; Macaca mulatta

Type:

Expression profiling by high throughput sequencing

7 related Platforms

134 Samples

Download data: GTF