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Items: 4

1.

Expression data by telomere elongation in vivo (xenograft)

(Submitter supplied) Limitless reproductive potential is one of the hallmarks of cancer cells1. This ability is accomplished by maintaining telomeres, which erosion otherwise causes cellular senescence or death. Human cancer cells often maintain shorter telomeres than do cells in surrounding normal tissues2-5. While most cancer cells activate telomerase, which can elongate telomeres6, it remains elusive why cancer cells keep telomeres short. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4964
Platform:
GPL570
16 Samples
Download data: CEL, TXT
Series
Accession:
GSE41559
ID:
200041559
2.
Full record GDS4964

Telomere-elongated, prostate cancer cells

Analysis of telomere-elongated PC-3 prostate cancer cells in the presence of exogenous human telomerase reverse transcriptase (hTERT). Forced elongation of telomeres promotes PC-3 cell differentiation. Results provide insight into the influence of telomere length on tumor malignancy.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets
Platform:
GPL570
Series:
GSE41559
16 Samples
Download data: CEL
3.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5669 Series
61 Related Platforms
174561 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570
4.

PC-3_basalhTERT_ShortTelomeres_mock_3

Organism:
Homo sapiens
Source name:
Human prostate cancer cell line
Platform:
GPL570
Series:
GSE41559
Dataset:
GDS4964
Download data: CEL
Sample
Accession:
GSM1019100
ID:
301019100
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