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Items: 17

1.

RNAseq data from Mesenchymal stem cells treated with TCDD or 1-methyl tryptophan

(Submitter supplied) Whole genome RNA-sequencing identified Nrf2, MAPK12 and IL-1a as important downstream targets of 1MT. We further demonstrate 1a1 and 1b1 activation by 1MT in IDO+ MSC following interferon-γ (IFNγ) activation, suggestive that 1MT-driven AHR signaling is uncoupled from IDO catalytic function. These observations support a novel paradigm by which AHR-activating compounds like 1MT can be used in cancer immunotherapy to stimulate a pro-inflammatory response, activating the body’s immune system to infiltrate and eradicate tumors.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
15 Samples
Download data: TXT
Series
Accession:
GSE95072
ID:
200095072

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina HiSeq 3000 (Homo sapiens)

Organism:
Homo sapiens
1087 Series
27237 Samples
Download data
Platform
Accession:
GPL21290
ID:
100021290

3.

BMH25-DL

Organism:
Homo sapiens
Source name:
MSCs_1MT (1mM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495750
ID:
302495750

SRA Run Selector

4.

BMH25-TCDD

Organism:
Homo sapiens
Source name:
MSCs_TCDD (10nM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495749
ID:
302495749

SRA Run Selector

5.

BMH25-NoRx

Organism:
Homo sapiens
Source name:
MSCs_vehicle (NoRx)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495748
ID:
302495748

SRA Run Selector

6.

BMH17-DL

Organism:
Homo sapiens
Source name:
MSCs_1MT (1mM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495747
ID:
302495747

SRA Run Selector

7.

BMH17-TCDD

Organism:
Homo sapiens
Source name:
MSCs_TCDD (10nM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495746
ID:
302495746

SRA Run Selector

8.

BMH17-NoRx

Organism:
Homo sapiens
Source name:
MSCs_vehicle (NoRx)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495745
ID:
302495745

SRA Run Selector

9.

BMH14-DL

Organism:
Homo sapiens
Source name:
MSCs_1MT (1mM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495744
ID:
302495744

SRA Run Selector

10.

BMH14-TCDD

Organism:
Homo sapiens
Source name:
MSCs_TCDD (10nM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495743
ID:
302495743

SRA Run Selector

11.

BMH14-NoRx

Organism:
Homo sapiens
Source name:
MSCs_vehicle (NoRx)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495742
ID:
302495742

SRA Run Selector

12.

BMH6-DL

Organism:
Homo sapiens
Source name:
MSCs_1MT (1mM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495741
ID:
302495741

SRA Run Selector

13.

BMH6-TCDD

Organism:
Homo sapiens
Source name:
MSCs_TCDD (10nM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495740
ID:
302495740

SRA Run Selector

14.

BMH6-NoRx

Organism:
Homo sapiens
Source name:
MSCs_vehicle (NoRx)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495739
ID:
302495739

SRA Run Selector

15.

BMH4-DL

Organism:
Homo sapiens
Source name:
MSCs_1MT (1mM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495738
ID:
302495738

SRA Run Selector

16.

BMH4-TCDD

Organism:
Homo sapiens
Source name:
MSCs_TCDD (10nM)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495737
ID:
302495737

SRA Run Selector

17.

BMH4-NoRx

Organism:
Homo sapiens
Source name:
MSCs_vehicle (NoRx)
Platform:
GPL21290
Series:
GSE95072
Download data
Sample
Accession:
GSM2495736
ID:
302495736

SRA Run Selector

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