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Items: 12

1.

Bach2 keeps homeostasis in lung by regulating inflammatory response and maintaining function of alveolar macrophage.

(Submitter supplied) Alveolar macrophages (AMs) of Bach2 KO mice show multiple alternations in their functions including lipid metabolism. We aimed to clarify the mechanism whereby deficiency of Bach2 impairs the function of AMs and ruins the homeostasis of lungs. Now we report that some cytokines produced from Bach2-deficient T cells alter the character of AMs and expression of Bach2 is necessary for AMs to maintain the function of lipid metabolism.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
10 Samples
Download data: CSV
Series
Accession:
GSE79558
ID:
200079558
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

Bach2_germline_KO_Sample 10

Organism:
Mus musculus
Source name:
Bach2_germline_KO
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098326
ID:
302098326
4.

WT_Sample 9

Organism:
Mus musculus
Source name:
WT
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098325
ID:
302098325
5.

Bach2-floxed CD4cre_KO_abnormal_Sample 8

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_KO_abnormal
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098324
ID:
302098324
6.

Bach2-floxed CD4cre_KO_normal_Sample 7

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_KO_normal
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098323
ID:
302098323
7.

Bach2-floxed CD4cre_control_Sample 6

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_control
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098322
ID:
302098322
8.

Bach2_germline_KO_Sample 5

Organism:
Mus musculus
Source name:
Bach2_germline_KO
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098321
ID:
302098321
9.

WT_Sample 4

Organism:
Mus musculus
Source name:
WT
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098320
ID:
302098320
10.

Bach2-floxed CD4cre_KO_abnormal_Sample 3

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_KO_abnormal
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098319
ID:
302098319
11.

Bach2-floxed CD4cre_KO_normal_Sample 2

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_KO_normal
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098318
ID:
302098318
12.

Bach2-floxed CD4cre_control_Sample 1

Organism:
Mus musculus
Source name:
Bach2-floxed CD4cre_control
Platform:
GPL17021
Series:
GSE79558
Download data
Sample
Accession:
GSM2098317
ID:
302098317
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Supplemental Content

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