GSE39203[Accession] - GEO DataSets - NCBI

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Select item 2000392031.

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing

(Submitter supplied) Epigenetic silencing of transposons by Piwi-interacting RNAs (piRNAs) constitutes an RNA-based genome defense mechanism. Piwi endonuclease action amplifies the piRNA pool by generating new piRNAs from target transcripts by a poorly understood mechanism. Here, we identified mouse Fkbp6 as a factor in this biogenesis pathway delivering piRNAs to the Piwi protein Miwi2. Mice lacking Fkbp6 derepress LINE1 (L1) retrotransposon and display reduced DNA methylation due to deficient nuclear accumulation of Miwi2. more...

Organism:: Mus musculus; Bombyx mori

Type:: Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL11002 GPL15780
24 Samples

Download data: TXT

Series

Accession:: GSE39203

ID:: 200039203

PubMed Similar studies SRA Run Selector

Select item 1000157802.

Illumina Genome Analyzer IIx (Bombyx mori)

Organism:: Bombyx mori

3 Series
27 Samples

Platform

Accession:: GPL15780

ID:: 100015780

Select item 1000110023.

Illumina Genome Analyzer IIx (Mus musculus)

Organism:: Mus musculus

895 Series
7710 Samples

Platform

Accession:: GPL11002

ID:: 100011002

Select item 3009580434.

Total small RNAs (14-33nt) P0 Fkbp6 KO

Organism:: Mus musculus

Source name:: Mouse testis, P0

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958043

ID:: 300958043

SRA Run Selector

Select item 3009580425.

Total small RNAs (14-33nt) P0 Fkbp6 Het

Organism:: Mus musculus

Source name:: Mouse testis, P0

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958042

ID:: 300958042

SRA Run Selector

Select item 3009580416.

MIWI2 IP E18 Tdrd1 Het

Organism:: Mus musculus

Source name:: Mouse testis, E18

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958041

ID:: 300958041

SRA Run Selector

Select item 3009580407.

MILI IP E18 Tdrd1 KO

Organism:: Mus musculus

Source name:: Mouse testis, E18

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958040

ID:: 300958040

SRA Run Selector

Select item 3009580398.

MILI IP E18 Tdrd1 Het

Organism:: Mus musculus

Source name:: Mouse testis, E18

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958039

ID:: 300958039

SRA Run Selector

Select item 3009580389.

MILI IP P10 Fkbp6 KO

Organism:: Mus musculus

Source name:: Mouse testis, P10

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958038

ID:: 300958038

SRA Run Selector

Select item 30095803710.

MILI IP P10 Fkbp6 Het

Organism:: Mus musculus

Source name:: Mouse testis, P10

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958037

ID:: 300958037

SRA Run Selector

Select item 30095803611.

MILI IP P0 Fkbp6 KO

Organism:: Mus musculus

Source name:: Mouse testis, P0

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958036

ID:: 300958036

SRA Run Selector

Select item 30095803512.

MILI IP P0 Fkbp6 Het

Organism:: Mus musculus

Source name:: Mouse testis, P0

Platform:: GPL11002
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958035

ID:: 300958035

SRA Run Selector

Select item 30095805813.

HA-Ago3 R→ K IP GA

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958058

ID:: 300958058

SRA Run Selector

Select item 30095805714.

HA-Ago3 R→ K IP control

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958057

ID:: 300958057

SRA Run Selector

Select item 30095805615.

HA-Ago3 ADH IP GA

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958056

ID:: 300958056

SRA Run Selector

Select item 30095805516.

HA-Ago3 ADH IP control

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958055

ID:: 300958055

SRA Run Selector

Select item 30095805417.

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958054

ID:: 300958054

SRA Run Selector

Select item 30095805318.

HA-Ago3 IP control

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958053

ID:: 300958053

SRA Run Selector

Select item 30095805219.

Strand-specific polyA+ RNAseq, GA

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958052

ID:: 300958052

SRA Run Selector

Select item 30095805120.

Strand-specific polyA+ RNAseq, control

Organism:: Bombyx mori

Source name:: Bombyx mori, BmN4 cells

Platform:: GPL15780
Series:: GSE39203

Download data: TXT

Sample

Accession:: GSM958051

ID:: 300958051

SRA Run Selector

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