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Items: 11

1.

Molecular characterization of immortalization of human MSCs by a combination of p53 knockdown and TERT overexpression

(Submitter supplied) Gene expression profile of p53 knockdown MSCs or p53 knockdown+TERT MSCs was compared with that of control MSCs. Our data show p53 knockdown prolongs the lifespan of MSCs, and a combination of p53 knockdown and TERT overexpression is sufficient to immortalize MSCs. The results provide important information about the molecular basis underlying p53 knockdown in MSCs and immortalization-related genes of MSCs.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6883
9 Samples
Download data: TXT
Series
Accession:
GSE28546
ID:
200028546
2.

Illumina HumanRef-8 v3.0 expression beadchip

(Submitter supplied) The HumanRef-8 v3.0 Expression BeadChip features up-to-date content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36.2, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. These should be submitted as part of a GEOarchive. more...
Organism:
Homo sapiens
8 DataSets
229 Series
3 Related Platforms
7128 Samples
Download data: BGX
Platform
Accession:
GPL6883
ID:
100006883
3.

Patient 3, P53KD, rep3

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706874
ID:
300706874
4.

Patient 3, P53KD+TERT, rep3

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD + TERT
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706873
ID:
300706873
5.

Patient 3, Control, rep3

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, control
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706872
ID:
300706872
6.

Patient 2, P53KD, rep2

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706871
ID:
300706871
7.

Patient 2, P53KD+TERT, rep2

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD + TERT
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706870
ID:
300706870
8.

Patient 2, Control, rep2

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, control
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706869
ID:
300706869
9.

Patient 1, P53KD, rep1

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706868
ID:
300706868
10.

Patient 1, P53KD+TERT, rep1

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, p53 KD + TERT
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706867
ID:
300706867
11.

Patient 1, Control, rep1

Organism:
Homo sapiens
Source name:
Mesenchymal stem cells, control
Platform:
GPL6883
Series:
GSE28546
Download data
Sample
Accession:
GSM706866
ID:
300706866
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Supplemental Content

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