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Items: 11

1.

Uremic toxin indoxyl sulfate induces trained immunity via the AhR-dependent arachidonic acid pathway in end-stage renal disease [RNAseq]

(Submitter supplied) Trained immunity is the long-term functional reprogramming of innate immune cells, which results in altered responses toward a secondary challenge. Despite indoxyl sulfate (IS) being a potent stimulus associated with chronic kidney disease (CKD)-related inflammation, its impact on trained immunity has not been explored. Here, we demonstrate that IS induces trained immunity in monocytes via epigenetic and metabolic reprogramming, resulting in augmented cytokine production. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
9 Samples
Download data: XLSX
Series
Accession:
GSE263024
ID:
200263024
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

GNF351-preteated IS-trained immunity-3, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183540
ID:
308183540
4.

GNF351-preteated IS-trained immunity-2, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183539
ID:
308183539
5.

GNF351-preteated IS-trained immunity-1, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183538
ID:
308183538
6.

IS-induced trained immunity-3, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183537
ID:
308183537
7.

IS-induced trained immunity-2, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183536
ID:
308183536
8.

IS-induced trained immunity-1, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183535
ID:
308183535
9.

control of trained immunity-3, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183534
ID:
308183534
10.

control of trained immunity-2, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183533
ID:
308183533
11.

control of trained immunity-1, 6 days

Organism:
Homo sapiens
Source name:
monocytes
Platform:
GPL24676
Series:
GSE263024
Download data
Sample
Accession:
GSM8183532
ID:
308183532
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Supplemental Content

db=gds|term=GSE263024[Accession]|query=20|qty=2|blobid=MCID_67377d5e24b250149148535e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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