GEO DataSets

(Submitter supplied) Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo: Transient maintenance of a pluripotent embryonic cell population followed by the onset of multi-lineage commitment is a fundamental aspect of development. However, molecular regulation of this transition is not well characterized in vivo. Here we demonstrate that the nuclear protein Geminin is required to restrain commitment and spatially restrict mesoderm, endoderm, and non-neural ectoderm to their proper locations in the Xenopus embryo. more...

Organism:

Xenopus laevis

Type:

Expression profiling by array

Platform:

GPL1318

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The Affymetrix GeneChip Xenopus laevis Genome Array can be used to study gene expression of over 14,400 Xenopus laevis transcripts. Sequence information for this array was selected from the following public data sources: GenBank (release 135.0, April 2003), dbEST (June 2003), and UniGene (Build 36, June 2003). more...

Organism:

Xenopus laevis

4 DataSets

47 Series

414 Samples

Download data