GSE240822[Accession] - GEO DataSets - NCBI

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Epigenetic regulation during cancer transitions across 11 tumour types.

(Submitter supplied) Chromatin accessibility plays an essential role in regulating gene expression and cellular identity, and its alterations have been implicated in driving oncogenic processes such as cancer initiation, progression, and metastasis1–4. While genetic aspects of cancer transitions have been explored, the role of epigenetic drivers remains less understood. To investigate the influence of chromatin architecture on cancer transitions, we generated an atlas of single-nucleus chromatin accessibility data (snATAC-seq) from 225 samples and matched single-cell/single-nucleus RNA expression (sc/snRNA-seq) from 206 samples across 11 cancer types. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24676
91 Samples

Download data: TAR, TSV

Series

Accession:: GSE240822

ID:: 200240822

PubMed Full text in PMC Similar studies

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

15281 Series
896303 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 3077100933.

C3N-00242-N_CPT0014470002_snRNA_ccRCC_NAT

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710093

ID:: 307710093

Select item 3077100924.

C3L-00079-N_CPT0001270002_snRNA_ccRCC_NAT

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710092

ID:: 307710092

Select item 3077100915.

C3L-01313-T1_CPT0086820004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710091

ID:: 307710091

Select item 3077100906.

C3L-00908-T1_CPT0086350004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710090

ID:: 307710090

Select item 3077100897.

C3L-01287-T1_CPT0079410004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710089

ID:: 307710089

Select item 3077100888.

C3N-00495-T1_CPT0078510004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710088

ID:: 307710088

Select item 3077100879.

C3N-01213-T1_CPT0075720013_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710087

ID:: 307710087

Select item 30771008610.

C3N-01200-N_CPT0075170013_snRNA_ccRCC_NAT

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710086

ID:: 307710086

Select item 30771008511.

C3N-01200-T1_CPT0075130004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710085

ID:: 307710085

Select item 30771008412.

C3L-00790-T1_CPT0065690004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710084

ID:: 307710084

Select item 30771008313.

C3L-01302-T1_CPT0063630004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710083

ID:: 307710083

Select item 30771008214.

C3N-00733-T1_CPT0025880013_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710082

ID:: 307710082

Select item 30771008115.

C3L-00610-T1_CPT0025110004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710081

ID:: 307710081

Select item 30771008016.

C3L-00917-T1_CPT0023690004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710080

ID:: 307710080

Select item 30771007917.

C3L-00583-T1_CPT0019130004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710079

ID:: 307710079

Select item 30771007818.

C3N-00242-T1_CPT0014450005_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710078

ID:: 307710078

Select item 30771007719.

C3N-00437-T1_CPT0012550012_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710077

ID:: 307710077

Select item 30771007620.

C3N-00317-T1_CPT0012280004_snRNA_ccRCC

Organism:: Homo sapiens

Source name:: Kidney

Platform:: GPL24676
Series:: GSE240822

Download data: TAR

Sample

Accession:: GSM7710076

ID:: 307710076

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