GSE234734[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2002347341.

Splicing targeting approaches highlight actionable vulnerabilities in advanced prostate cancer [22Rv1]

(Submitter supplied) To investigate if pharmacological inhibition of splicing could uncover novel actionable vulnerabilities in CRPC, we profiled the genome-wide transcriptional changes elicited in 22Rv1 cells by treatment with three drugs that inhibit the splicing through different molecular targets: i. Pladienolide B, that impairs the activity of SF3B1; ii. Indisulam that promote degradation of the splicing factor RBM39; iii. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL24676
12 Samples

Download data: TXT

Series

Accession:: GSE234734

ID:: 200234734

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000246762.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:: Homo sapiens

17145 Series
934634 Samples

Platform

Accession:: GPL24676

ID:: 100024676

Select item 3074740413.

22Rv1 Pladienolide B treated replica 3

Organism:: Homo sapiens

Source name:: 22Rv12

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474041

ID:: 307474041

SRA Run Selector

Select item 3074740404.

22Rv1 THZ531 treated replica 3

Organism:: Homo sapiens

Source name:: 22Rv11

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474040

ID:: 307474040

SRA Run Selector

Select item 3074740395.

22Rv1 Indisulam treated replica 3

Organism:: Homo sapiens

Source name:: 22Rv10

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474039

ID:: 307474039

SRA Run Selector

Select item 3074740386.

22Rv1 DMSO treated replica 3

Organism:: Homo sapiens

Source name:: 22Rv9

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474038

ID:: 307474038

SRA Run Selector

Select item 3074740377.

22Rv1 Pladienolide B treated replica 2

Organism:: Homo sapiens

Source name:: 22Rv8

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474037

ID:: 307474037

SRA Run Selector

Select item 3074740368.

22Rv1 THZ531 treated replica 2

Organism:: Homo sapiens

Source name:: 22Rv7

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474036

ID:: 307474036

SRA Run Selector

Select item 3074740359.

22Rv1 Indisulam treated replica 2

Organism:: Homo sapiens

Source name:: 22Rv6

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474035

ID:: 307474035

SRA Run Selector

Select item 30747403410.

22Rv1 DMSO treated replica 2

Organism:: Homo sapiens

Source name:: 22Rv5

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474034

ID:: 307474034

SRA Run Selector

Select item 30747403311.

22Rv1 Pladienolide B treated replica 1

Organism:: Homo sapiens

Source name:: 22Rv4

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474033

ID:: 307474033

SRA Run Selector

Select item 30747403212.

22Rv1 THZ531 treated replica 1

Organism:: Homo sapiens

Source name:: 22Rv3

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474032

ID:: 307474032

SRA Run Selector

Select item 30747403113.

22Rv1 Indisulam treated replica 1

Organism:: Homo sapiens

Source name:: 22Rv2

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474031

ID:: 307474031

SRA Run Selector

Select item 30747403014.

22Rv1 DMSO treated replica 1

Organism:: Homo sapiens

Source name:: 22Rv1

Platform:: GPL24676
Series:: GSE234734

Sample

Accession:: GSM7474030

ID:: 307474030

SRA Run Selector

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