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1.

Heritable human Polycomb silencing is locus-dependent and requires H2AK119ub1 self-propagation

(Submitter supplied) Heritable gene silencing is essential for the development of multicellular organisms. Polycomb repressive complexes 1 and 2 (PRC1 and 2) catalyze and recognize histone H2A lysine 119 mono-ubiquitination (H2AK119ub1) and histone H3 lysine 27 trimethylation (H3K27me3), respectively, to mediate heritable gene silencing, but the mechanism of inheritance is not fully understood. Using an inducible gene silencing strategy, we show that the epigenetic inheritance of Polycomb silencing in human cells is strongly dependent on local DNA sequences and chromatin environment. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
48 Samples
Download data: BW, FASTA
Series
Accession:
GSE209986
ID:
200209986

PubMed Full text in PMC Similar studies

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12534 Series
342121 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

WT1,FlagMTF2_EH,DoxycyclineRemoval, Flag, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412320
ID:
306412320

SRA Run Selector

4.

WT1,FlagMTF2_EH,DoxycyclineRemoval, Flag, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412319
ID:
306412319

SRA Run Selector

5.

WT1,FlagMTF2_EH,DoxycyclineAddition, Flag, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412318
ID:
306412318

SRA Run Selector

6.

WT1,FlagMTF2_EH,DoxycyclineAddition, Flag, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412317
ID:
306412317

SRA Run Selector

7.

WT1,FlagMTF2,DoxycyclineRemoval, Flag, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412316
ID:
306412316

SRA Run Selector

8.

WT1,FlagMTF2,DoxycyclineRemoval, Flag, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412315
ID:
306412315

SRA Run Selector

9.

WT1,FlagMTF2,DoxycyclineAddition, Flag, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412314
ID:
306412314

SRA Run Selector

10.

WT1,FlagMTF2,DoxycyclineAddition, Flag, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412313
ID:
306412313

SRA Run Selector

11.

WT1,FlagMTF2_EH,DoxycyclineRemoval, H3K27me3, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412312
ID:
306412312

SRA Run Selector

12.

WT1,FlagMTF2_EH,DoxycyclineRemoval, H3K27me3, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412311
ID:
306412311

SRA Run Selector

13.

WT1,FlagMTF2_EH,DoxycyclineAddition, H3K27me3, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412310
ID:
306412310

SRA Run Selector

14.

WT1,FlagMTF2_EH,DoxycyclineAddition, H3K27me3, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412309
ID:
306412309

SRA Run Selector

15.

WT1,FlagMTF2,DoxycyclineRemoval, H3K27me3, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412308
ID:
306412308

SRA Run Selector

16.

WT1,FlagMTF2,DoxycyclineRemoval, H3K27me3, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412307
ID:
306412307

SRA Run Selector

17.

WT1,FlagMTF2,DoxycyclineAddition, H3K27me3, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412306
ID:
306412306

SRA Run Selector

18.

WT1,FlagMTF2,DoxycyclineAddition, H3K27me3, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412305
ID:
306412305

SRA Run Selector

19.

WT1,MTF2KO,DoxycyclineRemoval, H3K27me3, Rep2

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412304
ID:
306412304

SRA Run Selector

20.

WT1,MTF2KO,DoxycyclineRemoval, H3K27me3, Rep1

Organism:
Homo sapiens
Source name:
HEK293FT
Platform:
GPL18573
Series:
GSE209986
Download data: BW
Sample
Accession:
GSM6412303
ID:
306412303

SRA Run Selector

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