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Items: 18

1.

Modeling Notch-induced tumor cell survival in the Drosophila ovary identifies cellular and transcriptional response to nuclear NICD accumulation

(Submitter supplied) Notch is a conserved developmental signaling pathway that is dysregulated in many cancer types, most often through constitutive activation. Tumor cells with nuclear accumulation of the active Notch receptor, NICD, generally exhibit enhanced survival while patients experience poorer outcomes. To understand the impact of NICD accumulation during tumorigenesis, we developed a tumor model using the Drosophila ovarian follicular epithelium. more...
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25244
16 Samples
Download data: CSV, MTX, ROBJ, TSV
Series
Accession:
GSE182505
ID:
200182505
2.

Illumina NovaSeq 6000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
788 Series
29663 Samples
Download data
Platform
Accession:
GPL25244
ID:
100025244
3.

72h lgl-KD+NICD-OE single-cell RNA-Seq dataset

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: MTX, ROBJ, TSV
Sample
Accession:
GSM5530541
ID:
305530541
4.

72h NICD-OE single-cell RNA-Seq dataset

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: MTX, ROBJ, TSV
Sample
Accession:
GSM5530540
ID:
305530540
5.

72h lgl-KD single-cell RNA-Seq dataset

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: MTX, ROBJ, TSV
Sample
Accession:
GSM5530539
ID:
305530539
6.

w1118 single-cell RNA-Seq dataset

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: MTX, ROBJ, TSV
Sample
Accession:
GSM5530538
ID:
305530538
7.

96h NICD+lgl-KD replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530537
ID:
305530537
8.

96h NICD+lgl-KD replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530536
ID:
305530536
9.

24h NICD+lgl-KD replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530535
ID:
305530535
10.

24h NICD+lgl-KD replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530534
ID:
305530534
11.

96h lgl-KD replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530533
ID:
305530533
12.

96h lgl-KD replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530532
ID:
305530532
13.

24h lgl-KD replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530531
ID:
305530531
14.

24h lgl-KD replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530530
ID:
305530530
15.

96h control replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530529
ID:
305530529
16.

96h control replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530528
ID:
305530528
17.

24h control replicate 2

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530527
ID:
305530527
18.

24h control replicate 1

Organism:
Drosophila melanogaster
Source name:
Whole ovarian tissue
Platform:
GPL25244
Series:
GSE182505
Download data: CSV
Sample
Accession:
GSM5530526
ID:
305530526
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Supplemental Content

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