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Items: 1 to 20 of 22

1.

Targeting the HuR oncogenic role with a new class of inhibitors of HuR dimerization

(Submitter supplied) Comprehensive meta-analysis and target screening confirmed that the mRNA-binding protein of ELAV-family HuR is oncogenic and universally upregulated in brain tumors, which highlight HuR as an universal chemotherapeutic target. HuR functionality in cancer cells is strictly dependent on HuR nuclear/cytoplasmic shuttling and dimerization; therefore, we developed a new class of inhibitors of HuR protein dimerization by utilizing medicinal chemistry techniques and reporter cell-based assay of HuR dimerization. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
20 Samples
Download data: XLSX
Series
Accession:
GSE158271
ID:
200158271

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12545 Series
342558 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

JX12 42127 3uM 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX12
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796181
ID:
304796181

SRA Run Selector

4.

JX12 DMSO 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX12
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796180
ID:
304796180

SRA Run Selector

5.

X1524 42127 3uM 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X1524
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796179
ID:
304796179

SRA Run Selector

6.

X1524 DMSO 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X1524
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796178
ID:
304796178

SRA Run Selector

7.

XD456 42127 3uM 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line XD456
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796177
ID:
304796177

SRA Run Selector

8.

XD456 DMSO 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line XD456
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796176
ID:
304796176

SRA Run Selector

9.

X14P 42127 3uM 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X14p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796175
ID:
304796175

SRA Run Selector

10.

X14P DMSO 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X14p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796174
ID:
304796174

SRA Run Selector

11.

JX22P 42127 3uM 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX22p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796173
ID:
304796173

SRA Run Selector

12.

JX22P DMSO 12H; second experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX22p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796172
ID:
304796172

SRA Run Selector

13.

JX12 42127 3uM 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX12
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796171
ID:
304796171

SRA Run Selector

14.

JX12 DMSO 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line JX12
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796170
ID:
304796170

SRA Run Selector

15.

X1524 42127 3uM 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X1524
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796169
ID:
304796169

SRA Run Selector

16.

X1524 DMSO 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X1524
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796168
ID:
304796168

SRA Run Selector

17.

XD456 42127 3uM 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line XD456
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796167
ID:
304796167

SRA Run Selector

18.

XD456 DMSO 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line XD456
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796166
ID:
304796166

SRA Run Selector

19.

X14P 42127 3uM 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X14p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796165
ID:
304796165

SRA Run Selector

20.

X14P DMSO 12H; first experiment

Organism:
Homo sapiens
Source name:
PDGx cell line X14p
Platform:
GPL18573
Series:
GSE158271
Download data
Sample
Accession:
GSM4796164
ID:
304796164

SRA Run Selector

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