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Items: 1 to 20 of 26

1.

Different mutant RUNX1 oncoprotein classes program alternate hematopoietic differentiation trajectories [RNA-Seq]

(Submitter supplied) Mutations of the hematopoietic master regulator RUNX1 cause acute myeloid leukaemia, familial platelet disorder and other haematological malignancies whose phenotypes and prognoses depend on the class of RUNX1 mutation. The biochemical behaviour of these oncoproteins and their ability to cause unique diseases has been well studied but the genomic basis of their differential action is unknown. To address this question we compared integrated phenotypic, transcriptomic and genomic data from cells expressing four types of RUNX1 oncoproteins in an inducible fashion during blood development from embryonic stem cells. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
24 Samples
Download data: TSV
Series
Accession:
GSE154622
ID:
200154622
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

Runx1Eto_PlusDox_HP_Rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676005
ID:
304676005
4.

Runx1Eto_PlusDox_HP_Rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676004
ID:
304676004
5.

Runx1Eto_PlusDox_HE2_Rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676003
ID:
304676003
6.

Runx1Eto_PlusDox_HE2_Rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676002
ID:
304676002
7.

Runx1Eto_NoDox_HP_Rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676001
ID:
304676001
8.

Runx1Eto_NoDox_HP_Rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4676000
ID:
304676000
9.

Runx1Eto_NoDox_HE2_Rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675999
ID:
304675999
10.

Runx1Eto_NoDox_HE2_Rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675998
ID:
304675998
11.

R204X_PlusDox_HP_rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675997
ID:
304675997
12.

R204X_PlusDox_HP_rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675996
ID:
304675996
13.

R204X_PlusDox_HE2_rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675995
ID:
304675995
14.

R204X_PlusDox_HE2_rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675994
ID:
304675994
15.

R204X_NoDox_HP_rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675993
ID:
304675993
16.

R204X_NoDox_HP_rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675992
ID:
304675992
17.

R204X_NoDox_HE2_rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675991
ID:
304675991
18.

R204X_NoDox_HE2_rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675990
ID:
304675990
19.

R201Q_PlusDox_Prog_Rep2

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675989
ID:
304675989
20.

R201Q_PlusDox_Prog_Rep1

Organism:
Mus musculus
Source name:
A2lox.cre mESC
Platform:
GPL19057
Series:
GSE154622 GSE154623
Download data: TSV
Sample
Accession:
GSM4675988
ID:
304675988
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Supplemental Content

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