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Items: 3

1.

Super-Enhancer-Associated Aortic Valve Stenosis Risk Locus 1p21.2 Alters NFATC2 Binding Site and Promotes Fibrogenesis [ATAC-Seq]

(Submitter supplied) Genome-wide association studies identified a strong signal for non coding variants at the 1p21.2 locus associated with calcific aortic valve stenosis (CAVS). Regulation at the locus and impact on the biology of the aortic valve is presently unknown. Integrative mapping of genetic association data was performed. The locus was evaluated by 3D genome mapping, analysis of atomic resolution data, DNA-binding assay and CRISPR activation (CRISPRa). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL20301
1 Sample
Download data: BW
Series
Accession:
GSE154510
ID:
200154510
2.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
3.

ATAC-seq in human aortic valve interstitial cells

Organism:
Homo sapiens
Source name:
Human aortic valve interstitial cells from non-mineralized aortic valves
Platform:
GPL20301
Series:
GSE154510 GSE154513
Download data: BW
Sample
Accession:
GSM4672357
ID:
304672357
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