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Items: 13

1.

THZ1-induced transcriptional changes in SMO inhibitor responsive and resistant mouse hedgehog-driven medulloblastoma cells

(Submitter supplied) Purpose: To assess THZ1-induced global changes of transcriptome of Hh-driven cancer Methods: SMB56 or SMB56-shSufu cells were mouse hedgehog-driven medulloblastoma cell lines that are either responsive or resistant to SMO inhibitor (GDC-0449). They were treated with 0.1 uM THZ1 or DMSO for 8 hours. 1 uM GDC-0449 treated SMB56 cells were included as control. Gene expression profiles were generated by RNAseq, in duplicate, using Hiseq3000. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21493 GPL21273
10 Samples
Download data: XLSX
Series
Accession:
GSE130485
ID:
200130485
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
4.

SMB56-GDC0449-2

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740929
ID:
303740929
5.

SMB56-GDC0449-1

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740928
ID:
303740928
6.

SMB56-THZ1-2

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740927
ID:
303740927
7.

SMB56-THZ1-1

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740926
ID:
303740926
8.

SMB56-DMSO-2

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740925
ID:
303740925
9.

SMB56-DMSO-1

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21273
Series:
GSE130485
Download data
Sample
Accession:
GSM3740924
ID:
303740924
10.

SMB56-shSufu-THZ1-2

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21493
Series:
GSE130485
Download data
Sample
Accession:
GSM3740933
ID:
303740933
11.

SMB56-shSufu-THZ1-1

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21493
Series:
GSE130485
Download data
Sample
Accession:
GSM3740932
ID:
303740932
12.

SMB56-shSufu-DMSO-2

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21493
Series:
GSE130485
Download data
Sample
Accession:
GSM3740931
ID:
303740931
13.

SMB56-shSufu-DMSO-1

Organism:
Mus musculus
Source name:
medulloblastoma
Platform:
GPL21493
Series:
GSE130485
Download data
Sample
Accession:
GSM3740930
ID:
303740930
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Supplemental Content

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