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Items: 8

1.

Cas9/sgRNA selective targeting of the P23H Rhodopsin mutant allele for treating retinitis pigmentosa by intravitreal AAV9.PHP.B-based delivery

(Submitter supplied) P23H is the most common mutation in the RHODOPSIN (RHO) gene leading to a dominant form of retinitis pigmentosa (RP), a rod photoreceptor degeneration that invariably causes vision loss. Specific disruption of the disease P23H RHO mutant while preserving the wild-type (WT) functional allele would be an invaluable therapy for this disease. However, various technologies tested in the past failed to achieve effective changes and consequently therapeutic benefits. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL16417
6 Samples
Download data: BEDGRAPH
Series
Accession:
GSE128579
ID:
200128579
2.

Illumina MiSeq (Mus musculus)

Platform
Accession:
GPL16417
ID:
100016417
3.

eletro2

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680570
ID:
303680570
4.

electro1

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680569
ID:
303680569
5.

Cont

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680568
ID:
303680568
6.

AAV3

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680567
ID:
303680567
7.

AAV2

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680566
ID:
303680566
8.

AAV1

Organism:
Mus musculus
Source name:
Retina
Platform:
GPL16417
Series:
GSE128579
Download data: BEDGRAPH
Sample
Accession:
GSM3680565
ID:
303680565
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Supplemental Content

db=gds|term=GSE128579[Accession]|query=1|qty=2|blobid=MCID_665250d66c053549897bd2e2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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