GSE125708[Accession] - GEO DataSets - NCBI

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Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain stuied at single-cell resolution

(Submitter supplied) The mammalian central nervous system (CNS) is capable of tolerating chronic hypoxia, but cell type-specific responses to this stress have not been systematically characterized. In the Norrin-knockout (NdpKO) mouse, a model of familial exudative vitreoretinopathy (FEVR), developmental hypovascularization of the retina produces chronic hypoxia of inner nuclear layer (INL) neurons and Muller glia. We have used single-cell RNA sequencing, untargeted metabolomics, and metabolite labeling from 13C-glucose to compare wild type and NdpKO retinas. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL17021 GPL19057
23 Samples

Download data: MTX, TSV, TXT

Series

Accession:: GSE125708

ID:: 200125708

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 1000190572.

Illumina NextSeq 500 (Mus musculus)

Organism:: Mus musculus

10286 Series
295783 Samples

Platform

Accession:: GPL19057

ID:: 100019057

Select item 1000170213.

Illumina HiSeq 2500 (Mus musculus)

Organism:: Mus musculus

11109 Series
299307 Samples

Platform

Accession:: GPL17021

ID:: 100017021

Select item 3035807444.

JH048_whole_brain_7d_hypoxia_R3

Organism:: Mus musculus

Source name:: adult whole brain, 7-day hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580744

ID:: 303580744

SRA Run Selector

Select item 3035807435.

JH047_whole_brain_7d_hypoxia_R2

Organism:: Mus musculus

Source name:: adult whole brain, 7-day hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580743

ID:: 303580743

SRA Run Selector

Select item 3035807426.

JH046_whole_brain_7d_hypoxia_R1

Organism:: Mus musculus

Source name:: adult whole brain, 7-day hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580742

ID:: 303580742

SRA Run Selector

Select item 3035807417.

JH045_whole_brain_48h_hypoxia_R3

Organism:: Mus musculus

Source name:: adult whole brain, 48-hour hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580741

ID:: 303580741

SRA Run Selector

Select item 3035807408.

JH044_whole_brain_48h_hypoxia_R2

Organism:: Mus musculus

Source name:: adult whole brain, 48-hour hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580740

ID:: 303580740

SRA Run Selector

Select item 3035807399.

JH043_whole_brain_48h_hypoxia_R1

Organism:: Mus musculus

Source name:: adult whole brain, 48-hour hypoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580739

ID:: 303580739

SRA Run Selector

Select item 30358073810.

JH042_whole_brain_normoxia_R3

Organism:: Mus musculus

Source name:: adult whole brain, normoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580738

ID:: 303580738

SRA Run Selector

Select item 30358073711.

JH041_whole_brain_normoxia_R2

Organism:: Mus musculus

Source name:: adult whole brain, normoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580737

ID:: 303580737

SRA Run Selector

Select item 30358073612.

JH040_whole_brain_normoxia_R1

Organism:: Mus musculus

Source name:: adult whole brain, normoxia

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580736

ID:: 303580736

SRA Run Selector

Select item 30358073513.

AR84_retina_Ndp_R2

Organism:: Mus musculus

Source name:: adult NdpKO whole retina

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580735

ID:: 303580735

SRA Run Selector

Select item 30358073414.

AR83_retina_Ndp_R1

Organism:: Mus musculus

Source name:: adult NdpKO whole retina

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580734

ID:: 303580734

SRA Run Selector

Select item 30358073315.

Organism:: Mus musculus

Source name:: adult NdpKO Muller glia Ribotag pulldown

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580733

ID:: 303580733

SRA Run Selector

Select item 30358073216.

Organism:: Mus musculus

Source name:: adult NdpKO Muller glia Ribotag pulldown

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580732

ID:: 303580732

SRA Run Selector

Select item 30358073117.

AR53_retina_WT_R2

Organism:: Mus musculus

Source name:: adult WT whole retina

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580731

ID:: 303580731

SRA Run Selector

Select item 30358073018.

AR49_retina_WT_R1

Organism:: Mus musculus

Source name:: adult WT whole retina

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580730

ID:: 303580730

SRA Run Selector

Select item 30358072919.

Organism:: Mus musculus

Source name:: adult WT Muller glia Ribotag pulldown

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580729

ID:: 303580729

SRA Run Selector

Select item 30358072820.

Organism:: Mus musculus

Source name:: adult WT Muller glia Ribotag pulldown

Platform:: GPL19057
Series:: GSE125708

Download data: TXT

Sample

Accession:: GSM3580728

ID:: 303580728

SRA Run Selector

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GSE125708[Accession] (26)
GEO DataSets
Acacia nilotica subsp. adstringens isolate 06-ANA01 trnL-trnF intergenic spacer ...
Acacia nilotica subsp. adstringens isolate 06-ANA01 trnL-trnF intergenic spacer and tRNA-Phe (trnF) gene, partial sequence; chloroplast
gi|55419748|gb|AY800454.1|

Nucleotide
Auchenipterichthys coracoideus voucher MCP<BRA>:46293 16S ribosomal RNA gene, pa...
Auchenipterichthys coracoideus voucher MCP<BRA>:46293 16S ribosomal RNA gene, partial sequence; mitochondrial
gi|1487881214|gb|MF595132.1|

Nucleotide

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