U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

Targeting 17q23 amplicon to overcome the resistance to anti-HER2 therapy in HER2+ breast cancer

(Submitter supplied) Amplification of chromosome 17q23 is a frequent genomic event that occurs in ~ 11% of human breast cancers. The 17q23 amplification is enriched in HER2+ breast cancers, which is significantly correlated with poor clinical outcomes. Previous studies have identified the oncogenic phosphatase WIP1 gene in the amplicon, which functions as a master inhibitor in DNA damage response. While the possibility of any other protein-coding oncogenes in the WIP1-containing 17q23 amplicon was ruled out, our analysis of human breast cancer genomics uncovered an oncogenic microRNA gene, MIR21, in a majority of the WIP1-containing amplicons. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
2 Samples
Download data: TXT
Series
Accession:
GSE119210
ID:
200119210

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 4000 (Mus musculus)

Organism:
Mus musculus
6556 Series
140923 Samples
Download data
Platform
Accession:
GPL21103
ID:
100021103

3.

MMTV-ErbB2;miR21-/-

Organism:
Mus musculus
Source name:
Mammary epithelial cells
Platform:
GPL21103
Series:
GSE119210
Download data: TXT
Sample
Accession:
GSM3360759
ID:
303360759

SRA Run Selector

4.

MMTV-ErbB2

Organism:
Mus musculus
Source name:
Mammary epithelial cells
Platform:
GPL21103
Series:
GSE119210
Download data: TXT
Sample
Accession:
GSM3360758
ID:
303360758

SRA Run Selector

Format
Sort by

Send to:

Choose Destination

Supplemental Content

Filters: Manage Filters

db=gds|term=GSE119210[Accession]|query=12|qty=2|blobid=MCID_671426b684112c3be248ae33|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Important Links

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets
Support Center