GSE113176[Accession] - GEO DataSets - NCBI

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Items: 15

Select item 2001131761.

Investigation of bivalently marked promoters in patient-derived colorectal cancer stem cells by ChIP-seq, chromatin accessibility by ATAC-seq, and differential regulation of gene expression following EZH2 inhibition using RNA-seq.

(Submitter supplied) We profiled changes in gene expression following EZH2 inhibition, in a patient-derived, cancer stem cell enriched model. Cells were treated with UNC1999, an EZH2 inhibitor, for 7 days, prior to processing for RNA-seq. In parallel, we identified H3K27me3 and H3K4me3 marked promoters using ChIP-seq at baseline in the same model, as well as chromatin accessibility using ATAC-seq.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL16791
13 Samples

Download data: BROADPEAK, CSV, NARROWPEAK

Series

Accession:: GSE113176

ID:: 200113176

PubMed Full text in PMC Similar studies

Select item 1000167912.

Illumina HiSeq 2500 (Homo sapiens)

Organism:: Homo sapiens

12172 Series
349192 Samples

Platform

Accession:: GPL16791

ID:: 100016791

Select item 3030985563.

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098556

ID:: 303098556

Select item 3030985554.

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098555

ID:: 303098555

Select item 3030985545.

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098554

ID:: 303098554

Select item 3030985536.

DMSO_Rep3_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098553

ID:: 303098553

Select item 3030985527.

DMSO_Rep2_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098552

ID:: 303098552

Select item 3030985518.

DMSO_Rep1_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098551

ID:: 303098551

Select item 3030985509.

UNC1999_Rep3_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098550

ID:: 303098550

Select item 30309854910.

UNC1999_Rep2_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098549

ID:: 303098549

Select item 30309854811.

UNC1999_Rep1_RNA_Seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098548

ID:: 303098548

Select item 30309854712.

H3K4me3_Rep2_ChIP-seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098547

ID:: 303098547

Select item 30309854613.

H3K27me3_Rep2_ChIP-seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098546

ID:: 303098546

Select item 30309854514.

H3K4me3_Rep1_ChIP-seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098545

ID:: 303098545

Select item 30309854415.

H3K27me3_Rep1_ChIP-seq

Organism:: Homo sapiens

Source name:: POP92

Platform:: GPL16791
Series:: GSE113176

Sample

Accession:: GSM3098544

ID:: 303098544

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