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Items: 12

1.

Sensory neurons co-opt classical immune signaling pathways to mediate chronic itch [6 NaV1.8+ Il4raF/F mice treated with MC903 compared to skin from 4 littermates]

(Submitter supplied) Mammals have evolved neurophysiologic reflexes such as coughing and scratching to expel invading pathogens and noxious environmental factors. It is well established that these responses are also associated with chronic inflammatory diseases such as asthma and atopic dermatitis. However, the mechanisms by which inflammatory pathways promote sensations such as itch remain poorly understood. Here, we show that type 2 cytokines directly stimulate sensory neurons in both mice and humans. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21493
10 Samples
Download data: TXT
Series
Accession:
GSE100397
ID:
200100397
2.

Illumina HiSeq 3000 (Mus musculus)

Platform
Accession:
GPL21493
ID:
100021493
3.

Experimental Rep6

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680306
ID:
302680306
4.

Experimental Rep5

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680305
ID:
302680305
5.

Experimental Rep4

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680304
ID:
302680304
6.

Experimental Rep3

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680303
ID:
302680303
7.

Experimental Rep2

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680302
ID:
302680302
8.

Experimental Rep1

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680301
ID:
302680301
9.

Littermate Rep4

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680300
ID:
302680300
10.

Littermate Rep3

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680299
ID:
302680299
11.

Littermate Rep2

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680298
ID:
302680298
12.

Littermate Rep1

Organism:
Mus musculus
Source name:
Whole Ear
Platform:
GPL21493
Series:
GSE100397
Download data: TXT
Sample
Accession:
GSM2680297
ID:
302680297
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Supplemental Content

db=gds|term=GSE100397[Accession]|query=17|qty=2|blobid=MCID_67352662b31eac71f544da04|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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