GEO DataSets

(Submitter supplied) The mechanisms leading to the vancomycin-intermediate Staphylococcus aureus (VISA) phenotype are incompletely understood. In an effort to identify VISA determinants, clinical hVISA strain MM66 and its 1st-step VISA mutants were compared. S. aureus microarrays, array data analysis protocols (NIAID's Pathogen Functional Genomics Resource Center), as well as comparative genomic sequencing (CGS) were utilized to determine VISA transcriptome alterations and mutations that define the MM66 VISA mechanism. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Platform:

GPL7072

8 Samples

Download data: TAV

(Submitter supplied) Genome-wide transcriptional profiling studies of the growth of bacteria with antimicrobial agents often reveals aspects of the drug-specific protective bacterial response. Fusidic acid is a steroid antimicrobial that inhibits protein synthesis by interfering with the release of elongation factor G (EF-G) after it has functioned in the translocation step. Two hundred and seventy two genes were both up- and down-regulated in a fusidic acid-susceptible strain of Staphylococcus aureus following challenge with 2 mg/L-1 fusidic acid for 15 min. more...

Organism:

Staphylococcus aureus

Type:

Expression profiling by array

Platform:

GPL7072

4 Samples

Download data: TAV

(Submitter supplied) This set includes 20224 elements on array in 96 grids. This is the condensed template of replicated (4x) features of PFGRC/JCVI Staphylococcus aureus version 4 array. For full template information please refer to: http://pfgrc.jcvi.org/index.php/microarray/array_description/staphylococcus_aureus/version4.html Protocol: Number of Grids - 96; Element Type - 70mer Oligonucleotide; Surface Coating - Epoxy; Oligonucleotides Designed - 4546; Replicate Oligo Printings - 4x; Controls - 500 Arabidopsis thaliana 70mers; 10 Arabidopsis thaliana amplicons.

Organism:

Staphylococcus aureus

2 Series

12 Samples

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