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Items: 1 to 20 of 24

1.

Expression data of EBV-positive and EBV-negative subclones of gastric adenocarcinoma cell line AGS

(Submitter supplied) Gastric cancer is one of the most common cancers worldwide. Epstein-Barr virus-associated gastric cancer accounts for approximately 10% of all gastric cancers. EBV expresses its own proteins and miRNAs (BART miRNAs) and regulates host gene expression. In this study, we examined the effect of EBV infection on host mRNA expression. Differential gene expression was analyzed between EBV-negative human gastric cancer cell line AGS and EBV-positive human gastric cancer cell line AGS-EBV.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
10 Samples
Download data: XLSX
Series
Accession:
GSE135644
ID:
200135644

PubMed Full text in PMC Similar studies Analyze with GEO2R

2.

TNF dependent induction of inhibitory pathways in CD4+ T cells in HIV and LCMV

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
4 related Platforms
82 Samples
Download data
Series
Accession:
GSE52185
ID:
200052185

PubMed Similar studies Analyze with GEO2R

3.

TNF dependent induction of inhibitory pathways in CD4+ T cells in HIV and LCMV [HIV-infected individuals]

(Submitter supplied) Chronic viral infections caused by HIV in humans or LCMV in mice are characterized by immunodeficiency and chronic inflammation. During chronification, T cells progressively lose effector functions, a process associated with immunoregulatory pathways and known as T-cell exhaustion. A link between ‘exhaustive’ T-cell reprogramming and chronic inflammation has not been established. Using a systems biology approach we demonstrate in HIV and LCMV infection that TNF, a prototypical mediator of chronic inflammation, functions upstream of major immunoregulatory pathways in T cells during chronic viral infection. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
20 Samples
Download data: TXT
Series
Accession:
GSE17606
ID:
200017606

Analyze with GEO2R

4.

Identification of Novel Serum Biomarkers for Early Decision of ST-elevation Myocardial Infarction

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6106 GPL6884
57 Samples
Download data
Series
Accession:
GSE61145
ID:
200061145

PubMed Full text in PMC Similar studies Analyze with GEO2R

5.

Expression data from blood samples of STEMI and Same STEMI patients after PIC

(Submitter supplied) We aim to determine blood transcriptome-based molecular signature of acute coronary syndrome (ACS), and to identify novel serum biomarkers for early stage ST-segment-elevation myocardial infarction (STEMI)
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
24 Samples
Download data: TXT
Series
Accession:
GSE61144
ID:
200061144

PubMed Full text in PMC Similar studies Analyze with GEO2R

6.

Whole genome expression data from pre-auricular and post-auricular skin tissues

(Submitter supplied) Photoaging is cumulative damage that is caused by chronic, repeated solar radiation exposure to skin. Its molecular mechanisms are poorly understood at the level of global gene expression.This study set out to uncover genes and functional modules involved in photoaging at the level of transcription, with the use of skin samples from Chinese women.Using the Illumina microarray platform, we compared the genome-wide expression profiles of 21 pairs of sun-exposed pre-auricular and sun-protected post-auricular skin samples from northern Chinese women.In total, 1,621 significantly regulated genes were identified from skin due to photoaging by microarray analysis. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6884 GPL6106
42 Samples
Download data: TXT
Series
Accession:
GSE38308
ID:
200038308

PubMed Full text in PMC Similar studies

7.

The discovery and validation of ten-gene prognostic classifier in gastric cancer by whole genome expression profiling

(Submitter supplied) The aim of this study is to identify and verify a prognosis set that is able to distinguish patient overall survival status based on whole genome expression profiling. Using Illumina HumanWG-6 beadarray, we analyzed the expression of 47,296 transcripts in two groups of gastric cancer patients who all underwent surgical resection. Thirty-nine of 46 samples in group one were used as a training set to discover candidates for overall survival prediction by using semi-supervised method, resulting in a panel of 10 genes as prognosis markers. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
72 Samples
Download data: TXT
Series
Accession:
GSE21983
ID:
200021983

PubMed Full text in PMC Similar studies Analyze with GEO2R

8.

Transcriptional profiles of pediatric SLE neutrophils and Healthy neutrophils cultured with SLE sera or Interferon

(Submitter supplied) Mature neutrophis were freshly isolated from blood of pediatric systemic lupus erythematosus (SLE) patients and healthy donors. Illumina microarray was used to assess transcriptional changes between SLE group and Control group. To uderstand further the gene expression difference between SLE and healthy neutrofils, neutrophils from healthy donors were cultured with autologous sera, SLE sera or Interferon and microarray data was used to compare with fresh SLE neutrophils.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
47 Samples
Download data: TXT
Series
Accession:
GSE27427
ID:
200027427

PubMed Full text in PMC Similar studies Analyze with GEO2R

9.

The role of vimentin in regulating genes related to EMT

(Submitter supplied) To study the biological and functional role of vimentin in maintenance of the mesenchymal phenotype of mammary epithelial cells, vimentin was silenced in the non-transformed MCF10A cells and vimentin-dependent changes in gene expression were analyzed.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
4 Samples
Download data: TXT
Series
Accession:
GSE17802
ID:
200017802

PubMed Similar studies Analyze with GEO2R

10.

Genome-wide comparison of AML leukemic stem cells (LSCs) and normal human hematopoietic stem cells (HSCs).

(Submitter supplied) Gene expression analysis of AML LSCs vs normal HSCs
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
17 Samples
Download data: TXT
Series
Accession:
GSE24395
ID:
200024395

PubMed Similar studies Analyze with GEO2R

11.

Peripheral blood gene-expression in depressed subjects with bipolar disorder vs healthy controls.

(Submitter supplied) Analysis of gene-expression changes in depressed subjects with bipolar disorder compared to healthy controls. Results provide information on pathways that may be involved in the pathogenesis of bipolar depression.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
35 Samples
Download data: TXT
Series
Accession:
GSE23848
ID:
200023848

PubMed Full text in PMC Similar studies Analyze with GEO2R

12.

Genome-wide analysis of SATB1 target genes in human T helper cells

(Submitter supplied) Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer and a transcription factor induced by interleukin-4 (IL-4) during the early T helper 2 (Th2) cell differentiation. In this study, we investigated the role of SATB1 in T helper cell differentiation by performing gene expression profiling of human differentiating Th cells in which expression of SATB1 was downregulated by RNA interference (RNAi). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6102 GPL2507 GPL6106
66 Samples
Download data: TXT
Series
Accession:
GSE17241
ID:
200017241

PubMed Full text in PMC Similar studies Analyze with GEO2R

13.

Anakinra in Systemic-onset Juvenile Idiopathic Arthritis

(Submitter supplied) Background: Systemic-Onset Juvenile Idiopathic Arthritis (SJIA) is a rare disease associated with dysregulated interleukin (IL)-1 activity. Objectives: To assess the efficacy and safety of Anakinra, an IL-1 receptor antagonist in SJIA and its effects on gene expression profiling. Methods: We conducted a multicenter, randomized, double-blind placebo-controlled trial. The primary objective was to compare the efficacy of a one-month treatment with anakinra (2 mg/kg subcutaneoulsy daily, maximum 100 mg) to a placebo between 2 groups of 12 SJIA patients each. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
85 Samples
Download data: TXT
Series
Accession:
GSE17590
ID:
200017590

PubMed Full text in PMC Similar studies Analyze with GEO2R

14.

Transcription profiling of Hepatitis C – specific natural CD25pos cells

(Submitter supplied) We reported previously that a proportion of natural CD25+ cells isolated from the PBMC of HCV patients can further upregulate CD25 expression in response to HCV peptides stimulation in vitro, and proposed that virus-specific regulatory T cells (Treg) were primed and expanded during the disease. Here we describe epigenetic analysis of the FOXP3 locus in HCV-responsive natural CD25+ cells and show that these cells are not activated conventional T cells expressing FOXP3, but hard-wired Treg with a stable FOXP3 phenotype and function. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
18 Samples
Download data: TXT
Series
Accession:
GSE16576
ID:
200016576

PubMed Full text in PMC Similar studies Analyze with GEO2R

15.

Subtypes of familial breast tumors revealed by expression and copy number profiling

(Submitter supplied) We analysed a cohort of 75 BRCA1, BRCA2 and non-BRCA1/2 breast tumors by gene expression profiling and found that 74% BRCA1 tumors were basal-like, 73% of BRCA2 tumors were luminal A or B, and 52% non-BRCA1/2 tumors were luminal A. Thirty-four tumors were also analysed by single nucleotide polymorphism-comparative genomic hybridization (SNP-CGH) arrays. Copy number data could predict whether a tumor was basal-like or luminal with high accuracy, but could not predict its mutation class. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL6986 GPL6106
109 Samples
Download data: TXT
Series
Accession:
GSE19177
ID:
200019177

PubMed Full text in PMC Similar studies Analyze with GEO2R

16.

Microvesicular mRNA profiling of SW480 human colorectal adenocarcinoma cells

(Submitter supplied) We analyzed mRNA profile of SW480-derived microvesicles using microarray Keywords: Microvesicular mRNA profiling
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
8 Samples
Download data: TXT
Series
Accession:
GSE9589
ID:
200009589

PubMed Full text in PMC Similar studies Analyze with GEO2R

17.

Genome functional screening identifies GAB2 as a key promoter of anchorage independence in normal and neoplastic cells

(Submitter supplied) Acquisition of independence from anchorage to the extracellular matrix is a critical event for onset and progression of solid cancers. To identify and characterize new genes conferring anchorage independence, we transduced MCF10A human normal breast cells with a retroviral cDNA expression library and selected them by growth in suspension. Microarray analysis targeted on library-derived transcripts revealed robust and reproducible enrichment, after selection, of cDNAs encoding the scaffolding adaptor Gab2. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6333 GPL6106
20 Samples
Download data: XLS
Series
Accession:
GSE18237
ID:
200018237

PubMed Similar studies Analyze with GEO2R

18.

Gene Expression Analysis of IgM+CD27+ B Cells in HCV-Infected Individuals with Mixed Cryoglobulinemia

(Submitter supplied) Analysis of IgM+CD27+ B cells in individuals with hepatitis C virus (HCV)-associated mixed cryoglobulinemia (MC). We have previously shown that HCV+MC+ individuals have clonal expansions of IgM+ memory B cells. This study aims to characterize differentially expressed genes in peripheral IgM+CD27+ B cells in HCV RNA+MC+ individuals, compared to HCV RNA+MC- subjects and HCV RNA- healthy controls. IgM+ B cells were isolated form donor PBMCs by immunomagnetic negative selection, and the CD27+ subset was further purified by positive selection. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
39 Samples
Download data: TXT
Series
Accession:
GSE18084
ID:
200018084

PubMed Full text in PMC Similar studies Analyze with GEO2R

19.

In vitro response of fibroblasts isolated from patients with immunodeficiencies

(Submitter supplied) Children with autosomal recessive deficiency suffer from life-threatening, often recurrent viral or bacterial infections. We have profiled transcriptional responses of fibroblast cell lines derived from patients deficient for key regulators of immune responses such as MYD88, IRAK4, UNC93B, STAT1 or NEMO. This systems immunology approach revealed distinct patterns or responsiveness to stimuli activating the Toll-like/IL1 Receptor pathway in either an MYD88-dependent (IL1B) or independent (poly(I:C)) fashion, or activating the TNF pathway. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL6106
72 Samples
Download data: TXT
Series
Accession:
GSE12124
ID:
200012124

PubMed Full text in PMC Similar studies Analyze with GEO2R

20.

Genomic Transcriptional Profiling Identifies a Blood Biomarker Signature for the Diagnosis of Septicemic Melioidosis

(Submitter supplied) Melioidosis is a severe infectious disease caused by Burkholderia pseudomallei, a gram-negative bacillus classified by the NIAID as a category B priority agent. Septicemia is the most common presentation of the disease with 40% mortality rate even with appropriate treatments. Faster diagnostic procedures are required to improve therapeutic response and survival rates. We have used microarray technology to generate genome-wide transcriptional profiles (>48,000 transcripts) of whole blood obtained from patients with septicemic melioidosis (n=32), patients with sepsis caused by other pathogens (n=31), and uninfected controls (n=29). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL6106 GPL6947
106 Samples
Download data: XLS
Series
Accession:
GSE13015
ID:
200013015

PubMed Full text in PMC Similar studies Analyze with GEO2R

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