GPL4603[RGSE] - GEO DataSets

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Items: 4

Select item 2000314001.

Sediment Series Upper Danube River (Sediment Extract and Freeze-Dried)

(Submitter supplied) The zebrafish embryo has repeatedly proved to be a useful model for the analysis of effects by environmental toxicants. This study was performed to investigate if an approach combining mechanism-specific bioassays with microarray techniques can obtain more in-depth insights into the ecotoxicity of complex pollutant mixtures as present, e.g., in freeze-dried whole sediment samples and their corresponding organic extracts in parallel. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL4603
8 Samples

Download data: GPR

Series

Accession:: GSE31400

ID:: 200031400

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000305942.

Sediment Extract Series River Rhine

(Submitter supplied) The zebrafish embryo has repeatedly proved to be a useful model for the analysis of effects by environmental toxicants. This proof-of-concept study was performed to investigate if an approach combining mechanism-specific bioassays with microarray techniques can obtain more in-depth insights into the ecotoxicity of complex pollutant mixtures as present, e.g., in sediment extracts. For this end, altered gene expression was compared to data from established bioassays as well as to results from chemical analysis. more...

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL4603
2 Samples

Download data: GPR, TXT

Series

Accession:: GSE30594

ID:: 200030594

Select item 2000307293.

Galanthamine hydrobromide 72h

(Submitter supplied) Microarray analysis of 72h 1mM Galanthamine hydrobromide treated embryos. At this concentration GAL causes myopathology without causing morbidity.

Organism:: Danio rerio

Type:: Expression profiling by array

Platform:: GPL4603
1 Sample

Download data: TAR, TXT

Series

Accession:: GSE30729

ID:: 200030729

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000093574.

biosensor-series

(Submitter supplied) Early life stages are generally most sensitive to toxic effects. Our knowledge on the action of man-made chemicals on the developing vertebrate embryo is, however, rather limited. We exposed zebrafish embryos to 11 of environmental toxicants and measured the changes in gene expression profiles by microarray. Our results demonstrate that the genome of the zebrafish embryo responds to toxicant exposure in a highly sensitive and specific manner. more...