GEO DataSets

(Submitter supplied) The impact of portal arterialization on the liver parenchyma was studied in a series of six pigs with aortoportal shunting of liver segments II, III and IV (and 6 sham animals). Gene expression in the arterialized segments was compared to expression in sham animals. Primary endpoints were gene expression profiles in the hyperperfused segments at sampling time points 1, 5, 10, 30, 60, 90 minutes and 2, 3, 4 and 6 hours after shunt opening. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3608

54 Samples

Download data: GPR

(Submitter supplied) Following parenchymal loss, the liver regenerates restoring normal mass and metabolic function. Prevailing theories on triggering events leading to regeneration include humoral, metabolic and flow-mediated mechanisms, the latter emphasizing the importance of shear stress mediated nitric oxide (NO) regulation. We aimed to investigate whether the grade of resection and hence the portal venous pressure and sinusoidal shear stress increase, would be reflected in the gene expression profiles in the liver remnant by employing a global porcine cDNA microarray chip with approximately 23 000 genes represented. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3608

32 Samples

Download data: GPR

(Submitter supplied) Boar taint is a major obstacle when using uncastrated male pigs for swine production. One of the main compounds causing this taint is androstenone, a pheromone produced in porcine testis. Here we use microarrays to study the expression of thousands of genes simultaneously in testis of high and low androstenone boars. The study allows identification of genes and pathways associated with elevated androstenone levels. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3608

60 Samples

Download data: CSV

(Submitter supplied) Background. Gene expression microarrays have been intensively applied to screen for genes involved in specific biological processes of interest such as diseases or responses to environmental stimuli. For mammalian species, cataloging of the global gene expression profiles in large tissue collections under normal conditions have been focusing on human and mouse genomes but is lacking for the pig genome. more...

Organism:

Sus scrofa

Type:

Expression profiling by array

Platform:

GPL3608

46 Samples

Download data

(Submitter supplied) DIAS_PIG_55K3_v1 consists of 55.548 features: 26.877 PCR products from cDNA clones and 867 control features spotted as neighbor duplicates in a 4 x 12 array with sub-arrays each consisting of 34 x 34 spots. The DNA fragments were amplified from cDNA clones selected from the cDNA libraries generated in the Sino-Danish Pig Genome Sequencing Consortium (Gorodkin et al.: Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 ESTs. more...

Organism:

Sus scrofa

4 Series

192 Samples

Download data: FASTA, GAL, TXT, ZIP