GEO DataSets

(Submitter supplied) Purpose: This study was undertaken to evaluate the effect of peritoneal fluid from subjects with differing stages of endometriosis on gene expression in endometrial stromal cells. Methods: Peritoneal fluid from subjects with minimal, moderate, and severe stages of endometriosis or without endometriosis (controls) was collected, filtered and separated from peritoneal cells. Telomerase – immortalized human endometrial stromal cells (T-HESC) were treated with the peritoneal fluid samples for 48 hours. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

12 Samples

Download data: TXT

(Submitter supplied) Objective: The objective of this study was to profile differential gene expression in three distinct patient groups. Study Design: The groups consisted of women with recurrent POP, women with primary POP and women without POP. Whole human genome DNA microarrays were used to evaluate differential gene expression in uterosacral ligament (USL) tissues. Results: 10 genes of interest were identified in USL. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

12 Samples

Download data

(Submitter supplied) we aimed to explore the molecular importance of the estrogen pathway through a detailed analysis of the transcriptomic profile of lactotroph tumors from 20 men and 10 women. We undertook gene expression analysis of the 30 selected lactotroph tumors following their pathological grading using the five-tiered classification.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

30 Samples

Download data: TXT

(Submitter supplied) Typically viral infections make the host more susceptible to subsequent bacterial infections by mechanisms that are incompletely defined. To identify host changes that occur in response to HK68 infection, gene expression of A549 lung epithelial cells were identified. Changes included an increase in transcripts encoding proteins with fibronectin-type III (FnIII) domains, such as fibronectin (Fn), tenascin N (TNN), and tenascin C (TNC). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

13 Samples

Download data: XLS

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL8227 GPL2895

45 Samples

Download data: TXT

(Submitter supplied) Background: Myocardial infarction (MI) is the single most critical event in coronary disease. Platelets partecipate in processes that precipitate acute MI, lack nuclear DNA but retain megakaryocyte mRNAs, thus their transcriptome could provide information preceding the coronary event. Our aim was to obtain a gene expression atlas of platelets from patients with their very first acute MI (FAMI) in order to identify potential markers of precipitating factors. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

38 Samples

Download data

(Submitter supplied) The transformation mechanism into a high-grade malignancy of SMZL has not been well studied. To define and compare the differentially expressed genes between primary SMZL cells at the different clinical periods, we analyzed the gene expression profiles using the CodeLink Human Whole Genome Bioarray.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

2 Samples

Download data: TXT

(Submitter supplied) [Objectives]: Neuropsychiatric systemic lupus erythematosus (NPSLE) is often difficult to diagnose and distinguish from those of other diseases, because no specific antibodies have yet been detected. [Methods]: We developed a novel proteomic strategy for identifying and profiling antigens in immune complexes (ICs) in the cerebrospinal fluid (CSF) of 26 NPSLE patients. We performed in vitro experiments using astrocytes and analyzed functional change by microarray. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

6 Samples

Download data: TXT

(Submitter supplied) Melanoma inhibitory activity (MIA) gene family is novel tumor-associated molecules. Although MIA gene family has several tumor progressive and/or suppressive functions, the detailed relevant signaling partners are unclear and investigated. In this study, we investigated the detailed MIA gene family-associated signaling using human oral squamous cell carcinoma cells.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

6 Samples

Download data: TXT

(Submitter supplied) Goal of the experiment: To examine differential gene expression in three ovarian cancer cell lines in the absence and presence of mifepristone. Brief description of the experiment: Hypothesis: The gene expression profile associated with a cytostatic response to Mifepristone will be similar between ovarian cancer cells regardless of their p53 status or sensitivity to Cisplatin. Aim: Evaluate the modifications in gene expression profile in ovarian cancer cells in response to a cytostatic concentration of Mifepristone against those in logarithmic phase of growth (Vehicle). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

18 Samples

Download data: TXT

(Submitter supplied) cervical cancer samples to test radiosensitivity Keywords: comparison between pre-irradiation and mid-irradiation status, correlation to prognosis

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

90 Samples

Download data: TXT

(Submitter supplied) KLF6 was overexpressed using an adenoviral delivery system. Overexpression was confirmed at 12, 24, 48 and 72 hours post infection by RT-PCR and Western Blot analysis. Codelink Whole genome microarrays were used to analyse changes in expression resulting from KLF6 overexpression.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

12 Samples

Download data: TXT

(Submitter supplied) We recently revealed that myeloid master regulator PU.1 directly represses metallothionein (MT)-1G through its epigenetic activity, but the functions of MT-1G in myeloid differentiation remain unknown. To clarify this, we established MT-1G-overexpressing acute promyelocytic leukemia NB4 (NB4MTOE) cells, and investigated whether MT-1G functionally contributes to all-trans retinoic acid (ATRA)-induced NB4 cell differentiation. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

2 Samples

Download data: TXT

(Submitter supplied) Kidney podocytes and their slit diaphragms contribute to prevent urinary protein loss. T cell from patients with systemic lupus erythematosus display increased expression of calcium/calmodulin kinase IV (CaMKIV). Here we evaluated the functional role of CaMKIV in lupus nephritis (LN) using kidney biopsy specimens and human podocyte cell line (AB8/13). We found that exposure of podocytes to IgG from LN patients resulted in entry of IgG into the cytoplasm. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

2 Samples

Download data: TXT

(Submitter supplied) Cytokines are implicated in the development of inflammatory diseases such as endometriosis. This project was designed to test the hypothesis that specific cytokines that are secreted by macrophages, such as tumor necrosis factor α (TNFα) and interleukin 1 beta (IL1β), cause gene expression changes in endometrial stromal cells. Telomerase-immortalized human endometrial stromal cells (T-HESC) were treated with TNFα (5ng/ml) ± IL1β (1ng/ml). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

12 Samples

Download data

(Submitter supplied) Objective: To examine the effects of the phytoestrogen metabolite, equol, on gene expression in the monkey iliac artery. Design: Eight ovariectomized cynomolgus monkeys were on a high fat diet for 6.5 years. The left iliac artery was biopsied prior to randomization to equol (0.0237 g/100 g chow, n=4) or vehicle (n=4) for 8 months. The right iliac artery was obtained at necropsy. Gene expression in the iliac arteries in response to equol was determined by DNA microarray and confirmed by real time RT-PCR. more...

Organism:

Homo sapiens; Macaca fascicularis

Type:

Expression profiling by array

Platform:

GPL2895

8 Samples

Download data: TXT

(Submitter supplied) Three stallions were treated with 0.1 mg/kg dexamethasone i.v. while three control stallions received an equivalent volume of saline. Serum testosterone dropped 60% in treated stallions at 12 h post-injection. Testes were collected 12 h post-injection and assessed for differential gene expression.

Organism:

Homo sapiens; Equus caballus

Type:

Expression profiling by array

Platform:

GPL2895

6 Samples

Download data: TXT

(Submitter supplied) Objective: To examine the effect of estradiol on gene expression in the monkey iliac arteries. Design: Eight ovariectomized cynomolgus monkeys were on a high fat diet for 6.5 years. The left iliac artery was biopsied before randomization to estradiol (1 mg Estrace® per day, n=4) or vehicle (n=4) for 8 months. The right iliac artery was obtained at necropsy. Gene expression in the iliac arteries in response to estradiol was determined by DNA microarray and confirmed by real time RT-PCR. more...

Organism:

Homo sapiens; Macaca fascicularis

Type:

Expression profiling by array

Platform:

GPL2895

8 Samples

Download data: TXT

(Submitter supplied) Peripheral blood mononuclear cells have emerged recently as pathology markers of cancer and other diseases, making possible their use as therapy predictors. Furthermore, the importance of the immune response in radiosensivity of solid organs led us to hypothesized that microarray gene expression profiling of peripheral blood mononuclear cells could identify patients with response to chemoradiation in rectal cancer. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

24 Samples

Download data: TXT

(Submitter supplied) Microarray gene expression profiling of central neurocytomas (CNs). Comparison between neurocytoma, pineocytoma (PC) and pineoblastoma (PB) relative to normal brain.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL2895

10 Samples

Download data