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Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signals

(Submitter supplied) Embryonic development yields many different cell types in response to just a few families of inductive signals. The property of signal-receiving cells that determines how they respond to inductive signals is known as competence, and it differs in different cell types. Here, we explore the ways in which maternal factors modify chromatin to specify initial competence in the frog Xenopus tropicalis. We identify early-engaged regulatory DNA sequences, and infer from them critical activators of the zygotic genome. more...
Organism:
Xenopus tropicalis
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
4 related Platforms
202 Samples
Download data: BED, BEDGRAPH, BW, TXT
Series
Accession:
GSE113186
ID:
200113186

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