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Items: 1 to 20 of 554

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1.

Protection against overfeeding-induced weight gain in mice is preserved in obesity but does not require FGF21 or MC4R

(Submitter supplied) Experimental overfeeding triggers homeostatic compensatory mechanisms that counteract weight gain. Here, we utilized intragastric overfeeding in mice to investigate the physiological and molecular responses to forced weight gain. Both lean and diet-induced obese (DIO) mice exhibited a potent and prolonged lowering of voluntary food intake following overfeeding-induced weight gain. Although overfeeding resulted in a marked increase in circulating fibroblast growth factor 21 (FGF21), experiments with FGF21 knockout (KO) mice demonstrated that FGF21 is dispensable for the homeostatic defense against experimental weight gain. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
24 Samples
Download data: CSV
Series
Accession:
GSE247825
ID:
200247825
2.

Transcriptome profiling of Phalaenopsis reveals that photoperiod regulates floral induction

(Submitter supplied) Floral induction; RNA-seq; Differentially transcribed Genes; WGSCN; qRT-PCR
Organism:
Phalaenopsis amabilis
Type:
Expression profiling by high throughput sequencing
Platform:
GPL33341
15 Samples
Download data: TXT
Series
Accession:
GSE229615
ID:
200229615
3.

Transcriptomic responses to cold stress in Dendrobium huoshanense C.Z. Tang et S.J. Cheng

(Submitter supplied) Dendrobium huoshanense C.Z. Tang et S.J. Cheng is a perennial epiphytic herb of family Orchidaceae, which main metabolites are polysaccharides, flavonoids, etc. Low temperature is the main environmental factor that limits the growth and development of plants, and even threatens the survival of plants. However, Changes that occur at the molecular level in response to low temperatures are poorly understood in D. more...
Organism:
Dendrobium huoshanense
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32838
6 Samples
Download data: FA, TXT
Series
Accession:
GSE217439
ID:
200217439
4.

Spatiotemporal transcriptomes of orchid flowers

(Submitter supplied) We performed spatial transcriptome sequencing of orchid to provide spatial cell atlas of floral organogenesis.
Organism:
Phalaenopsis aphrodite
Type:
Expression profiling by high throughput sequencing
Platform:
GPL32035
3 Samples
Download data: TAR
Series
Accession:
GSE198128
ID:
200198128
5.

Illumina sequencing reveals conserved and novel microRNAs involved in dendrobine biosynthesis in Dendrobium nobile

(Submitter supplied) Dendrobium plants are perennial herbs in the family Orchidaceae (Dendrobium Sw.). Due to protocorm can also produce plant-specific useful metabolites, protocorm is becoming a good substitute. MicroRNAs play essential roles in plant growth, development, and the response to environmental stresses, and they are widely used for prediction of molecular functions for biosynthesizing active comportments in medicinal plants. more...
Organism:
Dendrobium nobile; Dendrobium officinale
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL27018 GPL26011
3 Samples
Download data: TXT
Series
Accession:
GSE135444
ID:
200135444
6.

Transcriptional responses to maternal trichloroethylene and/or N-acetyl cysteine exposure in Wistar rat placental tissue

(Submitter supplied) Trichloroethylene (TCE) is a persistent and pervasive environmental contaminant. N-acetyl cysteine (NAC) is an antioxidant that may reduce TCE effects. Pregnant Wistar rats were exposed to 480 mg TCE mg/kg/day, 200 mg/kg/day NAC or co-exposure with both chemicals via ingestion (mini vanilla wafer) on gestation days 6-16 (tissue collection day). TCE- and/or NAC-induced changes to gene expression were evaluated in male and female rat placentae.
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25947
48 Samples
Download data: TXT
Series
Accession:
GSE168232
ID:
200168232
7.

High-density genetic map and genome-wide associaation studies of floral color traits in Phalaenopsis orchids

(Submitter supplied) The F1 population of Phalaenopsis Intermedia, which established from the cross between P. equestris and P. aphrodite was applied to build a high-density genetic map based on SSRs and SNPs from GBS methodology, with the digestion of by Hinp1 I and Hae III. In addition, another GBS was performed with enzymes ApeK I and Hae II to increase the SNP number for the GWAS analysis. We identified 10 SNPs highly associated with floral aesthetic trait, and among them, 4 were associated with flower color related. more...
Organism:
Phalaenopsis x intermedia
Type:
Other
Platforms:
GPL30232 GPL30233
4 Samples
Download data: TXT
Series
Accession:
GSE176215
ID:
200176215
8.

Diverging metabolic effects of two energy restricted diets differing in nutrient quality: a 12-week randomized controlled trial in subjects with abdominal obesity

(Submitter supplied) Background: Despite the established relation between energy restriction and metabolic health, the most beneficial nutrient composition of a weight-loss diet is still subject of debate. Objectives: The aim of the study was to examine the additional effects of nutrient quality on top of energy restriction(ER). Methods: A parallel-designed 12-week 25%ER dietary intervention study was conducted. Participants aged 40-70 years with abdominal obesity were randomized over three groups: a 25%ER high nutrient quality diet (n = 40); a 25%ER low nutrient quality diet (n = 40); or a habitual diet (n = 30). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17692
288 Samples
Download data: CEL
Series
Accession:
GSE197285
ID:
200197285
9.

Transcriptomic and metabolomic Profiling reveal the protective effect of Acanthopanax senticosus (Rupr. & Maxim.) Harms combined with Gastrodia elata Blume on cerebral ischemia-reperfusion injury

(Submitter supplied) In this work, we discussed the effects Acanthopanax senticosus Harms (ASE) combined with Gastrodia elata Blume (GEB) in the treatment of CIR injury. In pharmacodynamic studies, found that co-administration of ASE and GEB may improve neuronal injury and prevent neuronal apoptosis by reducing oxidative stress and inflammation, and also help prevent CIR injury. On the basis of our hypothesis, we combined the results of transcriptomic and metabonomic analyses and found that ASE and GEB could prevent cerebral ischemia-reperfusion injury induced by middle cerebral artery occlusion by targeting phenylalanine, pyrimidine, methionine, and sphingolipid metabolism. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22396
9 Samples
Download data: TXT
Series
Accession:
GSE160500
ID:
200160500
10.

Proteomic and transcriptomic analyses indicate metabolic changes and reduced defense responses in mycorrhizal roots of Oeceoclades maculata (Orchidaceae) collected in nature

(Submitter supplied) Orchids form an endomycorrhizal association with fungal symbionts mainly belonging to Basidiomycetes. The molecular events taking place in orchid mycorrhiza are poorly understood, although the cellular changes necessary to accommodate the fungus and to control nutrient exchange between the symbionts imply a modulation of gene expression. In this study, we used proteomic and transcriptomic approaches to identify changes in the steady-state levels of proteins and transcripts in roots of the green terrestrial orchid Oeceoclades maculata. more...
Organism:
Oeceoclades maculata
Type:
Expression profiling by high throughput sequencing
Platform:
GPL28979
6 Samples
Download data: FASTA, XLSX
Series
Accession:
GSE155822
ID:
200155822
11.

Small RNAs in monocots

(Submitter supplied) In monocots other than the cereals maize and rice, the repertoire and diversity of microRNAs (miRNAs) and the populations of phased, secondary, small interfering RNAs (phasiRNAs) are poorly characterized. To remedy this, we sequenced small RNAs (sRNAs) from vegetative and dissected inflorescence tissue in 28 phylogenetically diverse monocots and from several early-diverging angiosperm lineages, as well as publicly available data from 10 additional monocot species. more...
Organism:
Sorghum bicolor; Zea mays; Cyperus alternifolius; Zostera marina; Streptochaeta angustifolia; Elaeis guineensis; Nymphaea colorata; Echinodorus uruguayensis; Raddia brasiliensis; Prosthechea radiata; Liriope muscari; Musa acuminata var. zebrina; Musa ABB Group; Musa acuminata AAA Group; Acorus calamus; Setaria viridis; Canna indica; Anomochloa marantoidea; Kniphofia uvaria; Phalaenopsis equestris; Sagittaria montevidensis; Freycinetia cumingiana; Colocasia esculenta; Lemna gibba; Oryza glaberrima; Ananas comosus; Cocos nucifera; Phyllostachys edulis; Phoenix dactylifera; Hemerocallis lilioasphodelus; Pharus parvifolius; Tradescantia fluminensis; Goudaea ospinae
Type:
Non-coding RNA profiling by high throughput sequencing
34 related Platforms
195 Samples
Download data: TXT
Series
Accession:
GSE148762
ID:
200148762
12.

Small RNA profile from Cymbidium mosaic virus (CymMV) and Odontoglossum ringspot virus (ORSV) infected Phalaenopsis amabilis

(Submitter supplied) Viral siRNA generated from antiviral RNA silencing machinery was profiled using small RNA sequencing from Phalaenopsis orchid mixed infected with CymMV and ORSV
Organism:
Phalaenopsis amabilis
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL22989
10 Samples
Download data: TXT
Series
Accession:
GSE94083
ID:
200094083
13.

Vanilla planifolia Jacks., transcriptomic response towards Fusarium oxysporum f. sp. vanillae infection

(Submitter supplied) Upon exposure to unfavorable environmental conditions, plants need to respond quickly to maintain their homeostasis. For instance, physiological, biochemical and transcriptional changes occur during plant-pathogen interaction. In the case of Vanilla planifolia Jacks., a worldwide economically important crop, it is susceptible to Fusarium oxysporum f. sp. vanillae. This pathogen causes root and stem rot in vanilla plants that lead to plant death. more...
Organism:
Vanilla planifolia
Type:
Expression profiling by high throughput sequencing
Platform:
GPL26904
12 Samples
Download data: FASTA, TXT
Series
Accession:
GSE134155
ID:
200134155
14.

NCBI GEO Submission of human whole blood transcriptomes in response to a high-fat meal

(Submitter supplied) Modern humans spend most of their time having eaten recently. The purpose of the current project is to understand how the blood, which contains immune cells, responds in the hours after eating a meal that is moderately high in fat. We used a sequencing method to observe the expression of all the genes in blood cells in five participants who were each fed a high fat meal on three separate days. The results are reported in the manuscript, “Temporal changes in postprandial blood transcriptomes reveal subject-specific pattern of expression of innate immunity genes after a high-fat meal."
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
45 Samples
Download data: TXT
Series
Accession:
GSE127530
ID:
200127530
15.

Transcriptome deep sequencing to reveal the gene regulation of variegated mutation in Phalaenopsis aphrodite subsp. formosana

(Submitter supplied) Phalaenopsis aprodite subsp. formosana is one of the most important species for Phalaenopsis breeding. A mutant line with variegated leaf is found in this species. The green leaves bear unstable yellow sectors. In order to investigate the molecular mechanism of the variegated mutant line, we sequenced the transcriptome of variegated mutant by Illumina's Solexa sequencing technology. The sequence analysis results showed 22,598 unigenes by de novo assembly method, and the average unigene length was 1,286 bp. more...
Organism:
Phalaenopsis aphrodite subsp. formosana
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20931
2 Samples
Download data: FA, TXT
Series
Accession:
GSE73123
ID:
200073123
16.

De novo transcriptome assembly databases in the butterfly orchid Phalaenopsis equestris

(Submitter supplied) Orchidaceae are renowned for their spectacular flowers as well as other reproductive and ecological adaptations. After the genome of the tropical epiphytic orchid Phalaenopsis equestris was sequenced, we combined Trinity data for de novo assembly and Illumina HiSeq1500 data for RNA-Seq analysis to characterize the transcriptomes of four different organs for a better understanding of the molecular mechanisms driving these characteristics. more...
Organism:
Phalaenopsis equestris
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20642
4 Samples
Download data: FASTA, TXT
Series
Accession:
GSE70411
ID:
200070411
17.

Transcriptional profiling on leaves overexpressing Pha13 or Pha21 in Phalaenopsis aphrodite

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Phalaenopsis aphrodite
Type:
Expression profiling by array
Platform:
GPL22895
12 Samples
Download data: TXT
Series
Accession:
GSE93248
ID:
200093248
18.

Transcriptional profiling on leaves of Pha21 (PATC144963) overexpressed Phalaenopsis aphrodite

(Submitter supplied) To identify genes affected by Pha21, Pha21 was transiently overexpressed in leaves of P. aphrodite by agroinfiltration. The leaves of P. aphrodite infiltrated with agrobacterium carrying empty vector (without Pha21) was used as a control. Transcriptional profiling was analyzed using a customized oligonucleotide array with RNA extracted from Pha21 and empty vector overexpressed leaves of P. aphrodite. more...
Organism:
Phalaenopsis aphrodite
Type:
Expression profiling by array
Platform:
GPL22895
6 Samples
Download data: TXT
Series
Accession:
GSE93247
ID:
200093247
19.

Transcriptional profiling on leaves of Pha13 (PATC148746) overexpressed Phalaenopsis aphrodite

(Submitter supplied) To identify genes affected by Pha13, Pha13 was transiently overexpressed in leaves of P. aphrodite by agroinfiltration. The leaves of P. aphrodite infiltrated with agrobacterium carrying empty vector (without Pha13) was used as a control. Transcriptional profiling was analyzed using a customized oligonucleotide array with RNA extracted from Pha13 and empty vector overexpressed leaves of P. aphrodite. more...
Organism:
Phalaenopsis aphrodite
Type:
Expression profiling by array
Platform:
GPL22895
6 Samples
Download data: TXT
Series
Accession:
GSE93246
ID:
200093246
20.

Comparative transcriptome analysis of Gastrodia elata (Orchidaceae) in response to fungus symbiosis to identify gastrodin biosynthesis-related genes

(Submitter supplied) Gastrodia elata Blume (Orchidaceae) is an important Chinese medicine with several functional components. In the life cycle of G. elata, the orchid develops a symbiotic relationship with two compatible mycorrhizal fungi Mycena spp. and Armillaria mellea during seed germination to form vegetative propagation corm and vegetative growth to develop tubers, respectively. Gastrodin (p-hydroxymethylphenol-beta-D-glucoside) is the most important functional component in G. more...
Organism:
Gastrodia elata; Armillaria mellea
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20976 GPL20975
3 Samples
Download data: FA, MATRIX, TSV
Series
Accession:
GSE73633
ID:
200073633
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