Cobalt gluconate - GEO DataSets - NCBI

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Select item 2001791471.

CRISPR screen identifies loss of IFNγR signaling and downstream adhesion as a resistance mechanism to CAR T-cell cytotoxicity in solid tumors

(Submitter supplied) U87-CBG-GFP cells selected with blasticidin to stably express Cas9 were transduced with an MOI (< 1) of Brunello guide library (with puromycin resistance in the guide backbone). Cells were rested for 2 days then selected with puromycin antibiotic until the control, untransduced arm was killed (6-7 days). The guide-transduced cells were then pooled and replated in preparation for the screen. There were 12 arms to the screen, two control arms performed in technical duplicate and 8 sample arms from 6 normal donor CAR T-cells (2 were run in technical duplicate). more...

Organism:: Homo sapiens

Type:: Other

Platform:: GPL16791
1 Sample

Download data: CSV, TXT

Series

Accession:: GSE179147

ID:: 200179147

PubMed Similar studies SRA Run Selector

Select item 2001257392.

Transcriptome response of Gluconobacter oxydans against five typical aldehyde inhibitors

(Submitter supplied) Toxic inhibitory compounds from lignocellulose pretreatment are the major obstacle to achieve high bioconversion efficiency in biorefinery fermentations. This study shows a unique glucose oxidation catalysis of Gluconobacter oxydans with its gluconic acid productivity free of inhibitor disturbance. The microbial experimentations and the transcriptome analysis revealed that both the activity of the membrane-bound glucose dehydrogenase (mGDH) and the transcription level of the genes in periplasmic glucose oxidation respiratory chain of G. more...

Organism:: Gluconobacter oxydans

Type:: Expression profiling by array

Platform:: GPL26106
18 Samples

Download data: TXT

Series

Accession:: GSE125739

ID:: 200125739

Analyze with GEO2R

Select item 2001251233.

Systems-level Analysis of Oxygen Exposure in Zymomonas mobilis: Implications for Isoprenoid Production

(Submitter supplied) Zymomonas mobilis is an aerotolerant anaerobe and prolific ethanologen with attractive characteristics for industrial bioproduct generation. However, there is currently insufficient knowledge of the impact that environmental factors have on flux through industrially relevant biosynthetic pathways. Here, we examine the effect of oxygen exposure on metabolism and gene expression in Z. mobilis by combining targeted metabolomics, mRNA sequencing, and shotgun proteomics. more...

Organism:: Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821

Type:: Expression profiling by high throughput sequencing

Platform:: GPL26046
38 Samples

Download data: TXT

Series

Accession:: GSE125123

ID:: 200125123

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001157714.

Response of ECF sigma factor deletion mutants of Cupriavidus metallidurans to mixed metal ions (Co, Cu, Cd, Zn, Ni, 30 µM each)

(Submitter supplied) Response of Cupriavidus metallidurans CH34 and ECF deletion mutants to mixed metals

Organism:: Cupriavidus metallidurans CH34; Cupriavidus metallidurans

Type:: Expression profiling by array

Platform:: GPL16115
16 Samples

Download data: TXT

Series

Accession:: GSE115771

ID:: 200115771

PubMed Similar studies Analyze with GEO2R

Select item 2000238765.

Heavy metal resistance in Cupriavidus metallidurans CH34 is governed by an intricate transcriptional network

(Submitter supplied) Background: The high number of heavy metal resistance genes in the soil bacterium Cupriavidus metallidurans CH34 makes it an interesting model organism to study microbial responses to heavy metals. Results: In this study the transcriptional response of this bacterium was measured after challenging it to a wide range of sub-lethal concentrations of various essential or toxic metals. Considering the global transcriptional responses for each challenge as well as by identifying the overlap in upregulated genes between different metal responses, the sixteen metals could be clustered in three different groups. more...

Organism:: Cupriavidus metallidurans CH34

Type:: Expression profiling by array

Platform:: GPL4980
42 Samples

Download data: GPR

Series

Accession:: GSE23876

ID:: 200023876

PubMed Similar studies Analyze with GEO2R

Select item 2000112546.

Carbon nutrition of pathogenic and commensal E. coli

(Submitter supplied) Transcriptome profiling of E. coli MG1655, E. coli EDL933, E. coli ECOR26, and E. coli Nissle 1917 grown on mouse cecal mucus as carbon source The carbon sources that support growth of pathogenic E. coli O157:H7 in the mammalian intestine have not previously been investigated. In vivo, pathogenic E. coli EDL933 primarily grows as dispersed single cells within the mucus layer that overlies the mouse cecal epithelium. more...

Organism:: Escherichia coli str. K-12 substr. MG1655; Escherichia coli; Escherichia coli O157:H7 str. EDL933; Enterococcus faecalis V583; Bacillus anthracis; Escherichia coli CFT073; Bacteroides thetaiotaomicron VPI-5482; Escherichia coli O157:H7 str. Sakai; Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Type:: Expression profiling by array

Platform:: GPL6702
16 Samples

Download data: CEL, TXT

Series

Accession:: GSE11254

ID:: 200011254

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 3031894877.

CH34(delta rpoL,M,O) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 3

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189487

ID:: 303189487

Select item 3031894868.

CH34(delta rpoL,M,O) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 2

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189486

ID:: 303189486

Select item 3031894859.

CH34(delta rpoL,M,O) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 1

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189485

ID:: 303189485

Select item 30318948410.

CH34(delta rpoP,E,cnrH) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 3

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189484

ID:: 303189484

Select item 30318948311.

CH34(delta rpoP,E,cnrH) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 2

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189483

ID:: 303189483

Select item 30318948212.

CH34(delta rpoP,E,cnrH) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 1

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189482

ID:: 303189482

Select item 30318948113.

CH34(delta rpoQ,R) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 3

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189481

ID:: 303189481

Select item 30318948014.

CH34(delta rpoQ,R) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 2

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189480

ID:: 303189480

Select item 30318947915.

CH34(delta rpoQ,R) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 1

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189479

ID:: 303189479

Select item 30318947816.

CH34(delta rpoI,J,K) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 3

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189478

ID:: 303189478

Select item 30318947717.

CH34(delta rpoI,J,K) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 2

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189477

ID:: 303189477

Select item 30318947618.

CH34(delta rpoI,J,K) with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 1

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189476

ID:: 303189476

Select item 30318947519.

CH34 with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 3

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189475

ID:: 303189475

Select item 30318947420.

CH34 with 30 µM metal mix (Co,Ni,Zn,Cd,Cu), replicate 2

Organism:: Cupriavidus metallidurans

Source name:: cells

Platform:: GPL16115
Series:: GSE115771

Download data: TXT

Sample

Accession:: GSM3189474

ID:: 303189474

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