ClinVar

How to construct URLs to display data from ClinVar

Data in ClinVar can be accessed by URLs.  The result may be a single record, or a set of records that satisfy the query.  These examples are a sample only; any field or property listed in the help documentation can be used to build a URL by combining the base URL with the qualifier.

The base url is:

http://www.ncbi.nlm.nih.gov/clinvar/

which also takes you to ClinVar's home page.

Add the value in the Qualifier column to construct the final URL.

How to construct URLs to ClinVar

Type	Qualifier	Example
Variation accession	/variation/VCV000007105	http://www.ncbi.nlm.nih.gov/clinvar/variation/VCV000007105
Reference accession	RCV000007523	http://www.ncbi.nlm.nih.gov/clinvar/RCV000007523
Submission accession	?term=SCV000071392[clv_acc]	http://www.ncbi.nlm.nih.gov/clinvar/?term=SCV000071392[clv_acc]
AlleleID	?term=22144[alleleid]	http://www.ncbi.nlm.nih.gov/clinvar/?term=22144[alleleid]
Gene - symbol	?term=ABCC6[sym]	http://www.ncbi.nlm.nih.gov/clinvar/?term=ABCC6[sym]
Gene - MIM number	?term=603234[mim]	http://www.ncbi.nlm.nih.gov/clinvar/?term=603234[mim]
Gene - GeneID	?term=672[geneid]	http://www.ncbi.nlm.nih.gov/clinvar/?term=672[geneid]
Gene - HGNC id	?term=1884[hgnc] or ?term="HGNC:1884"[hgnc]	http://www.ncbi.nlm.nih.gov/clinvar/?term=1884[hgnc] http://www.ncbi.nlm.nih.gov/clinvar/?term="HGNC:1884"[hgnc]
GeneReviews NBK accession	?term=NBK1247	http://www.ncbi.nlm.nih.gov/clinvar/?term=NBK1247
Disease - Name	?term=noonan	http://www.ncbi.nlm.nih.gov/clinvar/?term=noonan
Disease - MIM	?term=264800[mim]	http://www.ncbi.nlm.nih.gov/clinvar/?term=264800[mim]
Disease - MedGen CUI	?term=C0033847	http://ncbi.nlm.nih.gov/clinvar/?term=C0033847
Variant - c. expression	?term=c.1018delG	http://www.ncbi.nlm.nih.gov/clinvar/?term=c.1018delG
VariationID	variation/7105	http://www.ncbi.nlm.nih.gov/clinvar/variation/7105
Interpretation (a property)	?term="clinsig pathogenic"[Properties]	http://www.ncbi.nlm.nih.gov/clinvar?term=%22clinsig%20pathogenic%22[Properties]
Combination of Interpretation and review status (both properties)	?term="clinsig pathogenic"[Properties] AND "revstat expert panel"[Properties]	http://www.ncbi.nlm.nih.gov/clinvar?term=%22clinsig%20pathogenic%22[Properties]%20AND%20%22revstat%20expert%20panel%22[Properties]
Chromosome position [as a range delimited by a colon (:)] Use [chrpos37] for GRCh37/hg19 and  [chrpos38] for GRCh38/hg38 Use [chrpos] for the current assembly	?term=17[chr] AND 43000000:44000000[chrpos37]	http://www.ncbi.nlm.nih.gov/clinvar/?term=17[chr]+AND+43000000:44000000[chrpos37]

This table provides a summary of common approaches to access ClinVar and represents only a subset of options that are available.  A table of the ClinVar field identifiers can be found here. To test other query options and determine how to convert them to URLs, please use the Search Builder tool (http://www.ncbi.nlm.nih.gov/clinvar/advanced). There you can review values that are in different fields of the public site, test queries, and save the URL that results in the type of link you want to create.