ClinVar

NM_002880.4(RAF1):c.1734C>T (p.Pro578=)

Gene:

RAF1:Raf-1 proto-oncogene, serine/threonine kinase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

3p25.2

Genomic location:

• Chr3: 12584916 (on Assembly GRCh38)
• Chr3: 12626415 (on Assembly GRCh37)

Preferred name:

NM_002880.4(RAF1):c.1734C>T (p.Pro578=)

HGVS:

• NC_000003.12:g.12584916G>A
• NG_007467.1:g.84264C>T
• NM_001354689.3:c.1794C>T
• NM_001354690.3:c.1734C>T
• NM_001354691.3:c.1491C>T
• NM_001354692.3:c.1491C>T
• NM_001354693.3:c.1635C>T
• NM_001354694.3:c.1551C>T
• NM_001354695.3:c.1392C>T
• NM_002880.4:c.1734C>TMANE SELECT
• NP_001341618.1:p.Pro598=
• NP_001341619.1:p.Pro578=
• NP_001341620.1:p.Pro497=
• NP_001341621.1:p.Pro497=
• NP_001341622.1:p.Pro545=
• NP_001341623.1:p.Pro517=
• NP_001341624.1:p.Pro464=
• NP_002871.1:p.Pro578=
• NP_002871.1:p.Pro578=
• LRG_413t1:c.1734C>T
• LRG_413t2:c.1794C>T
• LRG_413:g.84264C>T
• LRG_413p1:p.Pro578=
• LRG_413p2:p.Pro598=
• NC_000003.11:g.12626415G>A
• NM_002880.3:c.1734C>T
• NR_148940.3:n.2178C>T
• NR_148941.3:n.2124C>T
• NR_148942.3:n.2063C>T

This HGVS expression did not pass validation

Molecular consequence:

• NR_148940.3:n.2178C>T - non-coding transcript variant - [Sequence Ontology: SO:0001619]
• NR_148941.3:n.2124C>T - non-coding transcript variant - [Sequence Ontology: SO:0001619]
• NR_148942.3:n.2063C>T - non-coding transcript variant - [Sequence Ontology: SO:0001619]
• NM_001354689.3:c.1794C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354690.3:c.1734C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354691.3:c.1491C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354692.3:c.1491C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354693.3:c.1635C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354694.3:c.1551C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_001354695.3:c.1392C>T - synonymous variant - [Sequence Ontology: SO:0001819]
• NM_002880.4:c.1734C>T - synonymous variant - [Sequence Ontology: SO:0001819]