ClinVar

NM_004985.5(KRAS):c.80A>T (p.His27Leu)

Gene:

KRAS:KRAS proto-oncogene, GTPase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

12p12.1

Genomic location:

• Chr12: 25245305 (on Assembly GRCh38)
• Chr12: 25398239 (on Assembly GRCh37)

Preferred name:

NM_004985.5(KRAS):c.80A>T (p.His27Leu)

HGVS:

• NC_000012.12:g.25245305T>A
• NG_007524.2:g.10699A>T
• NM_001369786.1:c.80A>T
• NM_001369787.1:c.80A>T
• NM_004985.5:c.80A>TMANE SELECT
• NM_033360.4:c.80A>T
• NP_001356715.1:p.His27Leu
• NP_001356716.1:p.His27Leu
• NP_004976.2:p.His27Leu
• NP_203524.1:p.His27Leu
• LRG_344t1:c.80A>T
• LRG_344t2:c.80A>T
• LRG_344:g.10699A>T
• LRG_344p1:p.His27Leu
• LRG_344p2:p.His27Leu
• NC_000012.11:g.25398239T>A

This HGVS expression did not pass validation

Protein change:

H27L

Molecular consequence:

• NM_001369786.1:c.80A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001369787.1:c.80A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_004985.5:c.80A>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_033360.4:c.80A>T - missense variant - [Sequence Ontology: SO:0001583]