NM_002256.4(KISS1):c.*74_*75insCA AND not provided

NM_002256.4(KISS1):c.74_75insCA AND not provided

Germline classification:: Benign (1 submission)
Last evaluated:: Jun 19, 2018
Review status:: 1 star out of maximum of 4 stars
criteria provided, single submitter

Somatic classification of clinical impact:: None
Review status:: (0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided

Somatic classification of oncogenicity:: None
Review status:: (0/4) 0 stars out of maximum of 4 stars
no assertion criteria provided

Record status:: current
Accession:: RCV001671220.2

Allele description [Variation Report for NM_002256.4(KISS1):c.74_75insCA]

NM_002256.4(KISS1):c.74_75insCA

Gene:

KISS1:KiSS-1 metastasis suppressor [Gene - OMIM - HGNC]

Variant type:

Insertion

Cytogenetic location:

1q32.1

Genomic location:

Preferred name:

NM_002256.4(KISS1):c.*74_*75insCA

HGVS:

NC_000001.11:g.204190409_204190410insTG
NG_032151.1:g.11082_11083insCA
NM_002256.4:c.*74_*75insCAMANE SELECT
NC_000001.10:g.204159537_204159538insTG

Links:

dbSNP: rs200451423

NCBI 1000 Genomes Browser:

rs200451423

Molecular consequence:

NM_002256.4:c.*74_*75insCA - 3 prime UTR variant - [Sequence Ontology: SO:0001624]

Condition(s)

Synonyms:: none provided
Identifiers:: MedGen: C3661900

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CCNB2 cyclin B2 [Homo sapiens]
CCNB2 cyclin B2 [Homo sapiens]
Gene ID:9133

Gene
Gene Links for Protein (Select 54695786) (1)
Gene
mRNA-decapping enzyme subunit 2 [Cucumis sativus]
mRNA-decapping enzyme subunit 2 [Cucumis sativus]
gi|449449314|ref|XP_004142410.1|

Protein

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Submission Accession	Submitter	Review Status (Assertion method)	Clinical Significance (Last evaluated)	Origin	Method	Citations
SCV001885215	GeneDx	criteria provided, single submitter (GeneDx Variant Classification Process June 2021)	Benign (Jun 19, 2018)	germline	clinical testing	Citation Link

Submission Accession

Submitter

Review Status
(Assertion method)

Clinical Significance
(Last evaluated)

Origin

Method

Citations

SCV001885215

GeneDx

criteria provided, single submitter

(GeneDx Variant Classification Process June 2021)

Benign
(Jun 19, 2018)

germline

clinical testing

Citation Link

Help

Summary from all submissions

Ethnicity	Origin	Affected	Individuals	Families	Chromosomes tested	Number Tested	Family history	Method
not provided	germline	yes	not provided	not provided	not provided	not provided	not provided	clinical testing

Details of each submission

From GeneDx, SCV001885215.1

#	Ethnicity	Individuals	Chromosomes Tested	Family History	Method	Citations
1	not provided	not provided	not provided	not provided	clinical testing	not provided

#	Sample				Method		Observation
#	Origin	Affected	Number tested	Tissue	Purpose	Method	Individuals	Allele frequency	Families	Co-occurrences
1	germline	yes	not provided	not provided	not provided		not provided	not provided	not provided	not provided

Last Updated: Dec 24, 2023

ClinVar

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