ClinVar

NM_033360.4(KRAS):c.500G>C (p.Arg167Thr)

Gene:

KRAS:KRAS proto-oncogene, GTPase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

12p12.1

Genomic location:

• Chr12: 25215511 (on Assembly GRCh38)
• Chr12: 25368445 (on Assembly GRCh37)

Preferred name:

NM_033360.4(KRAS):c.500G>C (p.Arg167Thr)

HGVS:

• NC_000012.12:g.25215511C>G
• NG_007524.2:g.40493G>C
• NM_001369786.1:c.500G>C
• NM_001369787.1:c.451-5600G>C
• NM_004985.5:c.451-5600G>CMANE SELECT
• NM_033360.4:c.500G>C
• NP_001356715.1:p.Arg167Thr
• NP_203524.1:p.Arg167Thr
• LRG_344t1:c.451-5600G>C
• LRG_344t2:c.500G>C
• LRG_344:g.40493G>C
• LRG_344p2:p.Arg167Thr
• NC_000012.11:g.25368445C>G
• NG_007524.1:g.40410G>C
• NM_033360.3:c.500G>C

This HGVS expression did not pass validation

Protein change:

R167T

Links:

Molecular consequence:

• NM_001369787.1:c.451-5600G>C - intron variant - [Sequence Ontology: SO:0001627]
• NM_004985.5:c.451-5600G>C - intron variant - [Sequence Ontology: SO:0001627]
• NM_001369786.1:c.500G>C - missense variant - [Sequence Ontology: SO:0001583]
• NM_033360.4:c.500G>C - missense variant - [Sequence Ontology: SO:0001583]

Observations:

1