NM_000249.4(MLH1):c.677G>T (p.Arg226Leu) AND Hereditary cancer-predisposing syndrome
- Germline classification:
- Pathogenic/Likely pathogenic (4 submissions)
- Last evaluated:
- Mar 29, 2022
- Review status:
- Somatic classification
of clinical impact: - None
- Review status:
- Somatic classification
of oncogenicity: - None
- Review status:
- Record status:
- current
- Accession:
- RCV000708610.9
Allele description [Variation Report for NM_000249.4(MLH1):c.677G>T (p.Arg226Leu)]
NM_000249.4(MLH1):c.677G>T (p.Arg226Leu)
Condition(s)
- Name:
- Hereditary cancer-predisposing syndrome
- Synonyms:
- Neoplastic Syndromes, Hereditary; Tumor predisposition; Cancer predisposition; See all synonyms [MedGen]
- Identifiers:
- MONDO: MONDO:0015356; MeSH: D009386; MedGen: C0027672
Assertion and evidence details
Last Updated: Oct 20, 2024