ClinVar

NM_004985.5(KRAS):c.35G>T (p.Gly12Val)

Gene:

KRAS:KRAS proto-oncogene, GTPase [Gene - OMIM - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

12p12.1

Genomic location:

• Chr12: 25245350 (on Assembly GRCh38)
• Chr12: 25398284 (on Assembly GRCh37)

Preferred name:

NM_004985.5(KRAS):c.35G>T (p.Gly12Val)

Other names:

p.G12V:GGT>GTT; NP_004976.2:p.Gly12Val

HGVS:

• NC_000012.12:g.25245350C>A
• NG_007524.2:g.10654G>T
• NM_001369786.1:c.35G>T
• NM_001369787.1:c.35G>T
• NM_004985.5:c.35G>TMANE SELECT
• NM_033360.4:c.35G>T
• NP_001356715.1:p.Gly12Val
• NP_001356716.1:p.Gly12Val
• NP_004976.2:p.Gly12Val
• NP_203524.1:p.Gly12Val
• LRG_344t1:c.35G>T
• LRG_344t2:c.35G>T
• LRG_344:g.10654G>T
• LRG_344p1:p.Gly12Val
• LRG_344p2:p.Gly12Val
• NC_000012.11:g.25398284C>A
• NG_007524.1:g.10571G>T
• NM_004985.3:c.35G>T
• NM_004985.4:c.35G>T
• NM_033360.2:c.35G>T
• P01116:p.Gly12Val

This HGVS expression did not pass validation

Protein change:

G12V; GLY12VAL

Links:

UniProtKB: P01116#VAR_006840; OMIM: 190070.0006; OMIM: 190070.0026; dbSNP: rs121913529

NCBI 1000 Genomes Browser:

rs121913529

Molecular consequence:

• NM_001369786.1:c.35G>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_001369787.1:c.35G>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_004985.5:c.35G>T - missense variant - [Sequence Ontology: SO:0001583]
• NM_033360.4:c.35G>T - missense variant - [Sequence Ontology: SO:0001583]