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Items: 56

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
MFN2
(R364W)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease type 2
+3 more
GPathogenic
COL11A1
(R352W +2 more)
Single nucleotide variant
(missense variant +2 more)
not provided
GConflicting classifications of pathogenicity
CACNA1S
(R364W)
Single nucleotide variant
(missense variant)
Hypokalemic periodic paralysis, type 1
+1 more
GLikely benign
LAMB3
(R364W)
Single nucleotide variant
(missense variant)
Junctional epidermolysis bullosa gravis of Herlitz
+2 more
GConflicting classifications of pathogenicity
ACTN2
(R572W +1 more)
Single nucleotide variant
(missense variant)
Cardiovascular phenotype
+4 more
GConflicting classifications of pathogenicity
NLRP3
(R366W +1 more)
Single nucleotide variant
(missense variant)
Familial amyloid nephropathy with urticaria AND deafness
+5 more
GUncertain significance
ALK
(R1432W +1 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
TTC7A
(R10W +2 more)
Single nucleotide variant
(missense variant)
Multiple gastrointestinal atresias
GUncertain significance
FBXO11
(R364W +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
IMMT
(R267W +19 more)
Single nucleotide variant
(missense variant +2 more)
not specified
GUncertain significance
TRIP12
(R322W +2 more)
Single nucleotide variant
(missense variant +1 more)
Clark-Baraitser syndrome
GUncertain significance
MLPH
(R479W +3 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
SCLY, UBE2F-SCLY
(R364W)
Single nucleotide variant
(non-coding transcript variant +1 more)
not specified
GUncertain significance
TGFBR2
(R364W +8 more)
Single nucleotide variant
(missense variant)
not provided
+5 more
GConflicting classifications of pathogenicity
USP4
(R411W +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ZMYND10
(R369W +1 more)
Single nucleotide variant
(missense variant)
Primary ciliary dyskinesia
+1 more
GBenign/Likely benign
PRICKLE2
(R364W)
Single nucleotide variant
(missense variant)
Progressive myoclonic epilepsy type 5
GUncertain significance
ILDR1
(R453W +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
IFT122
(R364W +6 more)
Single nucleotide variant
(missense variant)
Cranioectodermal dysplasia 1
GUncertain significance
DOK7
(R364W +2 more)
Single nucleotide variant
(3 prime UTR variant +1 more)
not provided
+2 more
GUncertain significance
COL25A1
(R360W +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
MTREX
(R364W)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
MBOAT1
(R364W)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
SCUBE3
(R365W +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
PGM3
(R255W +2 more)
Single nucleotide variant
(missense variant +1 more)
Immunodeficiency 23
GUncertain significance
DDC
(R319W +4 more)
Single nucleotide variant
(missense variant)
Deficiency of aromatic-L-amino-acid decarboxylase
+2 more
GPathogenic/Likely pathogenic
CYP7A1, LOC126860400
(R364W)
Single nucleotide variant
(missense variant)
CYP7A1-related disorder
GUncertain significance
KIF12
(R226W +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
CARD9
(R364W)
Single nucleotide variant
(missense variant)
Predisposition to invasive fungal disease due to CARD9 deficiency
GUncertain significance
RET
(R694W +17 more)
Single nucleotide variant
(missense variant)
Multiple endocrine neoplasia type 2A
+4 more
GUncertain significance
AGAP6, TIMM23B-AGAP6
(R565W +1 more)
Single nucleotide variant
(non-coding transcript variant +1 more)
not specified
GUncertain significance
SUFU
(R364W)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+4 more
GUncertain significance
IRF7
(R364W +2 more)
Single nucleotide variant
(missense variant)
Immunodeficiency 39
GUncertain significance
PNPLA2
(R364W)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
MAPK8IP1
(R364W)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
XRRA1
(R349W +9 more)
Single nucleotide variant
(3 prime UTR variant +2 more)
not specified
GUncertain significance
KMT2A
(R331W +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
SLC6A13
(R364W +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
RAB3IP
(R158W +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
F7
(R342W +2 more)
Single nucleotide variant
(missense variant +1 more)
Abnormality of coagulation
GLikely pathogenic
AP1G2, AP1G2-AS1
(R235W +2 more)
Single nucleotide variant
(5 prime UTR variant +2 more)
not specified
GUncertain significance
LMF1
(R147W +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
ABAT
(R377W +7 more)
Single nucleotide variant
(missense variant)
Gamma-aminobutyric acid transaminase deficiency
GUncertain significance
TAT, TAT-AS1
(R364W)
Single nucleotide variant
(missense variant)
Tyrosinemia type II
GUncertain significance
CHRNE, LOC130060041
(R364W)
Single nucleotide variant
(missense variant)
Congenital myasthenic syndrome 4A
GUncertain significance
DLG4, LOC126862479
(R364W +5 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
SHISA6
(R415W +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
MYO19
(R364W)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
BRCA1
(R1426W +75 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
DTNA
(R659W +12 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
TCF4
(R576W +21 more)
Single nucleotide variant
(missense variant)
Pitt-Hopkins syndrome
GPathogenic
LMNB2
(R364W)
Single nucleotide variant
(missense variant)
Lipodystrophy, partial, acquired, susceptibility to
+1 more
GUncertain significance
WDR62
(R364W +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
BCKDHA
(R364W +1 more)
Single nucleotide variant
(missense variant)
Maple syrup urine disease
GUncertain significance
SNRNP70
(R364W +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TXNRD2
(R364W +3 more)
Single nucleotide variant
(missense variant +1 more)
Primary dilated cardiomyopathy
GUncertain significance
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