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Items: 86

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
DNAJC16
(R141H +1 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
C1QB
(R139H +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
LOC126805765, NEXN
(R77H +1 more)
Single nucleotide variant
(missense variant)
Cardiovascular phenotype
+2 more
GUncertain significance
AMPD2
(R141H +4 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
AP4B1-AS1, PTPN22
(R141H)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
AVPR1B
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
WNT3A
(R141H)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
DCTN1
(R141H +6 more)
Single nucleotide variant
(missense variant +1 more)
Neuronopathy, distal hereditary motor, type 7B
+3 more
GUncertain significance
UXS1
(R28H +4 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
POMGNT2
(R141H)
Single nucleotide variant
(missense variant)
Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 8
+1 more
GLikely benign
QARS1
(R130H +1 more)
Single nucleotide variant
(missense variant +1 more)
Diffuse cerebral and cerebellar atrophy - intractable seizures - progressive microcephaly syndrome
GUncertain significance
IQCF1
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
YTHDC2
(R141H)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
PPP2CA
(R206H +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
HARS1
(R141H +6 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
GABRB2
(R141H)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
PSMB8
(R141H +1 more)
Single nucleotide variant
(missense variant)
Autoinflammatory syndrome
GUncertain significance
FAM135A
(R98H +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
CEP57L1
(R158H +4 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
FAM184A
(R141H +1 more)
Single nucleotide variant
(missense variant)
not specified
GLikely benign
TNFAIP3
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
SUN1
(R141H +4 more)
Single nucleotide variant
(missense variant +2 more)
Emery-Dreifuss muscular dystrophy
GUncertain significance
NPC1L1
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CTTNBP2
(R141H +1 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
OPN1SW
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
FANCG
(R141H)
Single nucleotide variant
(missense variant)
Fanconi anemia
+1 more
GUncertain significance
NPR2
(R141H)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
BICD2
(R141H)
Single nucleotide variant
(missense variant)
Autosomal dominant childhood-onset proximal spinal muscular atrophy with contractures
GUncertain significance
WDR38
(R141H +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SH2D3C
(R138H +4 more)
Single nucleotide variant
(5 prime UTR variant +1 more)
not specified
GUncertain significance
SPTAN1
(R129H +1 more)
Single nucleotide variant
(missense variant)
Early infantile epileptic encephalopathy with suppression bursts
GUncertain significance
LAMC3
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
MSRB2
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ACBD5
(R141H +4 more)
Single nucleotide variant
(missense variant)
not provided
GBenign
KCNQ1
(R231H +2 more)
Single nucleotide variant
(missense variant)
not provided
+7 more
GPathogenic
LDHA
(R112H +1 more)
Single nucleotide variant
(missense variant +2 more)
Inborn genetic diseases
GUncertain significance
WT1
(R158H +8 more)
Single nucleotide variant
(missense variant +2 more)
Meacham syndrome
+6 more
GConflicting classifications of pathogenicity
COMMD9
(R99H +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
BEST1
(R141H +2 more)
Single nucleotide variant
(missense variant +2 more)
Retinal dystrophy
+2 more
GPathogenic/Likely pathogenic
CARNS1
(R141H +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ITFG2
(R141H)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
ING4
(R120H +4 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
LOC126861443, MFAP5
(R116H +4 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
PDE3A
(R141H +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
POLR3B
(R141H +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
ATP6V0A2
(R141H)
Single nucleotide variant
(missense variant)
ALG9 congenital disorder of glycosylation
+3 more
GUncertain significance
LOC132090059, PUS1
(R113H +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
CBY2
(R141H +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CAB39L
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
BRF1
(R114H +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
IQCH
(R145H +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
RNF151
(R141H)
Single nucleotide variant
(3 prime UTR variant +1 more)
not specified
GUncertain significance
PAQR4
(R169H +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
PMM2
(R141H)
Single nucleotide variant
(missense variant)
Focal segmental glomerulosclerosis
+4 more
GPathogenic/Likely pathogenic
WWOX
(R141H +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+1 more
GUncertain significance
TUBB3
(R141H +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
XAF1
(R141H +6 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
TMEM95
(R133H +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TP53
(R273H +3 more)
Single nucleotide variant
(missense variant)
Li-Fraumeni syndrome
+1 more
GPathogenic
OOncogenic
SLFN11
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
BRCA1
(R252H +20 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+3 more
GConflicting classifications of pathogenicity
PNPO
(R141H)
Single nucleotide variant
(missense variant)
Pyridoxal phosphate-responsive seizures
+1 more
GUncertain significance
SGCA
(R141H)
Single nucleotide variant
(missense variant +1 more)
not specified
+1 more
GUncertain significance
FDXR
(R141H +5 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
RHBDF2
(R112H +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
REEP6
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
TLE2
(R141H +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
LONP1
(R205H +2 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
TUBB4A
(R141H +3 more)
Single nucleotide variant
(missense variant)
Hypomyelinating leukodystrophy 6
GUncertain significance
ZNF823
(R141H +1 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
DCAF15
(R160H +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
LPAR2
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SARS2
(R141H)
Single nucleotide variant
(missense variant +1 more)
not specified
GLikely benign
SLC4A11
(R141H +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
RALY
(R141H +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CNBD2
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TOMM34
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
DYRK1A
(R141H +2 more)
Single nucleotide variant
(missense variant)
DYRK1A-related intellectual disability syndrome
GBenign
GET1, GET1-SH3BGR
(R107H +2 more)
Single nucleotide variant
(non-coding transcript variant +2 more)
not specified
GUncertain significance
LRRC3
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ACO2
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PPARA
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CDKL5, RS1
(R141H)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GPathogenic/Likely pathogenic
DMD
(R149H +3 more)
Single nucleotide variant
(missense variant)
Cardiovascular phenotype
+2 more
GUncertain significance
NYX
(R141H)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
UBL4A
(R141H)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
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