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Items: 33

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
CLCNKA
(Q19*)
Single nucleotide variant
(nonsense)
Bartter disease type 4B
+2 more
GConflicting classifications of pathogenicity
MUTYH
(Q33* +1 more)
Single nucleotide variant
(nonsense +2 more)
Familial adenomatous polyposis 2
GConflicting classifications of pathogenicity
AP4B1
(Q19* +1 more)
Single nucleotide variant
(nonsense +1 more)
Hereditary spastic paraplegia 47
GPathogenic
LMNA, LOC126805877
(Q131* +2 more)
Single nucleotide variant
(nonsense)
Charcot-Marie-Tooth disease type 2
GPathogenic
LAMB3
(Q19*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
POMC
(Q19*)
Single nucleotide variant
(nonsense)
not provided
GLikely pathogenic
CYP1B1
(Q19*)
Single nucleotide variant
(nonsense)
Anterior segment dysgenesis 6
+3 more
GPathogenic
LOC129936244, XPC
(Q19*)
Single nucleotide variant
(5 prime UTR variant +2 more)
Xeroderma pigmentosum, group C
+1 more
GPathogenic/Likely pathogenic
PDE6B, PDE6B-AS1
(Q298* +1 more)
Single nucleotide variant
(nonsense +1 more)
Retinal dystrophy
+3 more
GPathogenic
TECRL
(Q19*)
Single nucleotide variant
(nonsense)
Catecholaminergic polymorphic ventricular tachycardia 3
GUncertain significance
RMND1
(Q189* +1 more)
Single nucleotide variant
(nonsense)
Mitochondrial disease
GPathogenic
BBS9
(Q19* +1 more)
Single nucleotide variant
(nonsense +3 more)
Bardet-Biedl syndrome 9
+2 more
GPathogenic
GCK
(Q17* +2 more)
Single nucleotide variant
(nonsense)
Maturity-onset diabetes of the young type 2
GLikely pathogenic
PLPBP
(Q106* +2 more)
Single nucleotide variant
(nonsense +1 more)
Epilepsy, early-onset, vitamin B6-dependent
GPathogenic
TRPS1
(Q19* +3 more)
Single nucleotide variant
(nonsense)
Trichorhinophalangeal dysplasia type I
GLikely pathogenic
CYP11B1, LOC110673972
(Q19*)
Single nucleotide variant
(nonsense)
Deficiency of steroid 11-beta-monooxygenase
+1 more
GPathogenic/Likely pathogenic
C5
(Q19*)
Single nucleotide variant
(nonsense +1 more)
not provided
+3 more
GPathogenic
COQ4
(Q19*)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
GLikely pathogenic
ERCC6
(Q19*)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
ABCC8
(Q19*)
Single nucleotide variant
(nonsense +1 more)
Hyperinsulinemic hypoglycemia, familial, 1
GPathogenic
SLC6A5
(Q253* +1 more)
Single nucleotide variant
(nonsense)
not provided
GLikely pathogenic
RPS26
(Q19*)
Single nucleotide variant
(nonsense)
Diamond-Blackfan anemia 10
GPathogenic
RCBTB1
(Q19* +1 more)
Single nucleotide variant
(nonsense +1 more)
not provided
GPathogenic
MAX
(Q19*)
Single nucleotide variant
(5 prime UTR variant +2 more)
Hereditary pheochromocytoma-paraganglioma
+1 more
GPathogenic/Likely pathogenic
BBS4
(Q19*)
Single nucleotide variant
(nonsense +2 more)
Bardet-Biedl syndrome 4
+1 more
GPathogenic/Likely pathogenic
ADGRG1
(Q142* +3 more)
Single nucleotide variant
(nonsense +1 more)
Bilateral frontoparietal polymicrogyria
GPathogenic
BRCA1
(Q19*)
Single nucleotide variant
(nonsense +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BCKDHA
(Q19*)
Single nucleotide variant
(nonsense)
Maple syrup urine disease
GPathogenic
GNAS
(Q19*)
Single nucleotide variant
(nonsense +1 more)
not provided
GPathogenic
PRODH
(Q127* +1 more)
Single nucleotide variant
(nonsense)
Proline dehydrogenase deficiency
GPathogenic
COX7B
(Q19*)
Single nucleotide variant
(nonsense)
Linear skin defects with multiple congenital anomalies 2
GPathogenic
DNAAF6
(Q19*)
Single nucleotide variant
(nonsense)
DNAAF6-related disorder
GUncertain significance
MECP2
(Q19* +1 more)
Single nucleotide variant
(nonsense +1 more)
Inborn genetic diseases
+1 more
GPathogenic
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