U.S. flag

An official website of the United States government

Format
Items per page
Sort by
Choose Destination

Search results

Items: 100

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
EMC1, EMC1-AS1
(T327S +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
MUTYH
(A305G +7 more)
Single nucleotide variant
(missense variant +1 more)
Familial adenomatous polyposis 2
GUncertain significance
ACADM
(A152G +4 more)
Single nucleotide variant
(missense variant)
Medium-chain acyl-coenzyme A dehydrogenase deficiency
+1 more
GUncertain significance
LMNA
(A283G +5 more)
Single nucleotide variant
(missense variant)
Primary dilated cardiomyopathy
GUncertain significance
ADCY10, DCAF6
(P366R +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
LIN9
(P212R +5 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
AGT
(S305C)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
ZBTB18
(T296S +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
SOS1
(P298R +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
ABCG5, DYNC2LI1
(T305R)
Single nucleotide variant
(missense variant +1 more)
Sitosterolemia 2
+1 more
GPathogenic/Likely pathogenic
MSH2
(S176C +6 more)
Single nucleotide variant
(missense variant +2 more)
Lynch syndrome
GUncertain significance
MSH6
(T175S +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
MSH6
(S156* +8 more)
Single nucleotide variant
(nonsense +2 more)
Hereditary cancer-predisposing syndrome
GPathogenic
MSH6
(T607R +2 more)
Single nucleotide variant
(missense variant)
Hereditary nonpolyposis colorectal neoplasms
+4 more
GUncertain significance
NRXN1
(T1303R +13 more)
Single nucleotide variant
(missense variant)
Pitt-Hopkins-like syndrome 2
GUncertain significance
TIA1
(A316G +11 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GBenign/Likely benign
TIA1
(P164R +11 more)
Single nucleotide variant
(missense variant +1 more)
Welander distal myopathy
GUncertain significance
ANKMY1
(P216R +2 more)
Single nucleotide variant
(missense variant +3 more)
not specified
GUncertain significance
RARB
(T368S +5 more)
Single nucleotide variant
(missense variant +1 more)
Microphthalmia, syndromic 12
+1 more
GConflicting classifications of pathogenicity
MLH1
(P403R +5 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
FOXP1
(T406S +4 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GConflicting classifications of pathogenicity
POLQ
(S305C)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SLC41A3
(A295G +3 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
OPA1
(P429R +9 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
PDGFRA
(A305G +2 more)
Single nucleotide variant
(missense variant)
Gastrointestinal stromal tumor
+1 more
GUncertain significance
FBXW7
(T267R +2 more)
Single nucleotide variant
(missense variant)
FBXW7-related disorder
GUncertain significance
PDE4D
(S113C +11 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
ERCC8
(S152* +2 more)
Single nucleotide variant
(nonsense)
not provided
GPathogenic
HEXB
(T305R +1 more)
Single nucleotide variant
(missense variant)
Sandhoff disease
GLikely benign
APC
(T315R +6 more)
Single nucleotide variant
(missense variant)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
APC
(A447G +10 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
ALDH7A1
(A305G +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+2 more
GUncertain significance
PCDHB7, PCDHB@
(A305G)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
LCP2
(P305R)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ZSCAN16, ZSCAN16-AS1
(T276R +1 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
AGER
(P275R +2 more)
Single nucleotide variant
(missense variant +2 more)
not specified
GUncertain significance
SUN1
(T184S +50 more)
Single nucleotide variant
(missense variant +1 more)
Emery-Dreifuss muscular dystrophy
GUncertain significance
PMS2
(S276C +19 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
MATCAP2
(S318C +5 more)
Single nucleotide variant
(missense variant)
not specified
GLikely benign
IKZF1
(A249G +11 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
EGFR, LOC126860048
(S297C +3 more)
Single nucleotide variant
(missense variant)
EGFR-related lung cancer
GUncertain significance
EGFR
(T519R +3 more)
Single nucleotide variant
(missense variant)
EGFR-related lung cancer
GUncertain significance
ZNF735
(A305G)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
PCLO
(P305R)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
FLNC
(A305G)
Single nucleotide variant
(missense variant)
Distal myopathy with posterior leg and anterior hand involvement
+3 more
GUncertain significance
PRKAG2
(S305C +4 more)
Single nucleotide variant
(missense variant)
Cardiomyopathy
+2 more
GUncertain significance
PRAG1
(P305R)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
HGSNAT
(P369R +2 more)
Single nucleotide variant
(missense variant)
Retinitis pigmentosa 73
+1 more
GUncertain significance
NBN
(S387C +1 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GConflicting classifications of pathogenicity
FREM1
(S1769C +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
PTCH1
(T390S +3 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
CORO2A
(P305R)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
RALGPS1
(P335R +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
DOLK
(S305C)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
ADAMTS13
(S305C +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
ZFYVE27
(S332C +21 more)
Single nucleotide variant
(missense variant +1 more)
Spastic paraplegia
GUncertain significance
DEAF1
(T305S +2 more)
Single nucleotide variant
(missense variant)
not provided
GConflicting classifications of pathogenicity
CHRNA10
(T305S +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TRIM5, TRIM6
(P305R +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
ELP4, PAX6
(P222R +4 more)
Single nucleotide variant
(3 prime UTR variant +3 more)
Aniridia 1
GUncertain significance
WT1
(T129R +9 more)
Single nucleotide variant
(missense variant +2 more)
Drash syndrome
+3 more
GUncertain significance
MEN1
(A340G +2 more)
Single nucleotide variant
(missense variant)
Multiple endocrine neoplasia, type 1
GUncertain significance
SYTL2
(T231S +5 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ATM
(S305*)
Single nucleotide variant
(nonsense)
Ataxia-telangiectasia syndrome
+1 more
GPathogenic
DLAT
(T193S +7 more)
Single nucleotide variant
(missense variant +1 more)
Pyruvate dehydrogenase E2 deficiency
GUncertain significance
CACNA1C
(A305G)
Single nucleotide variant
(missense variant)
Long QT syndrome
GUncertain significance
TNFRSF1A
(P305R +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PTPRB
(A305G +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
OAS1
(P305R +2 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
PACS2
(P305R +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
BLM
(P305R)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
HBA-LCR, NPRL3
(P204R +3 more)
Single nucleotide variant
(missense variant)
Epilepsy, familial focal, with variable foci 3
GUncertain significance
GRIN2A
(S305C)
Single nucleotide variant
(missense variant)
Landau-Kleffner syndrome
GUncertain significance
SLC38A8
(S305C)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
ELAC2
(P305R +1 more)
Single nucleotide variant
(missense variant)
Combined oxidative phosphorylation defect type 17
GUncertain significance
TP53I13
(P262R +3 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
MSL1
(P552R +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
BRCA1
(P1498R +75 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(S1496* +75 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(S1183C +75 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(S1457* +75 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(A1340G +63 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(S1450* +58 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(P178R +20 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary breast ovarian cancer syndrome
GUncertain significance
USH1G
(S305C +1 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
TCF4
(S435* +13 more)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
GPathogenic
ATP8B3
(T252R +1 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
SMARCA4
(P305R)
Single nucleotide variant
(missense variant +1 more)
Rhabdoid tumor predisposition syndrome 2
GUncertain significance
VASP
(S305C)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
RBCK1
(P347R +2 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+1 more
GUncertain significance
PIGU
(A305G)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
SON
(T305S)
Single nucleotide variant
(missense variant +2 more)
See cases
GLikely benign
TXNRD2
(T276R +4 more)
Single nucleotide variant
(missense variant +1 more)
Primary dilated cardiomyopathy
+1 more
GUncertain significance
CHEK2
(S372C +4 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
EIF3L
(T255S +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
KIAA0930
(P300R +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
OTC
(P305R)
Single nucleotide variant
(missense variant)
Ornithine carbamoyltransferase deficiency
GPathogenic
UBA1
(S305C)
Single nucleotide variant
(missense variant)
Infantile-onset X-linked spinal muscular atrophy
GUncertain significance
PGK1
(S305C)
Single nucleotide variant
(missense variant)
not provided
GLikely benign
CUL4B
(S127C +3 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
Format
Items per page
Sort by
Choose Destination