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Items: 25

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
TMEM147
Single nucleotide variant
(splice acceptor variant)
Inborn genetic diseases
GUncertain significance
TMEM147
(T55fs +1 more)
Deletion
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(F57fs +1 more)
Microsatellite
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(I68T +1 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TMEM147
(G83R +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TMEM147
(I99L +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TMEM147
(T108A +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TMEM147
Single nucleotide variant
(intron variant)
Motor delay
+4 more
GPathogenic
TMEM147
Single nucleotide variant
(intron variant)
TMEM147-related disorder
GBenign
TMEM147
Single nucleotide variant
(splice acceptor variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(R75W +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TMEM147
(W130* +1 more)
Single nucleotide variant
(nonsense +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(I133N +1 more)
Single nucleotide variant
(missense variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(N140fs +1 more)
Duplication
(frameshift variant +1 more)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(N140S +1 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
TMEM147
(Y113* +2 more)
Single nucleotide variant
(nonsense)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(R117W +2 more)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(V108fs +2 more)
Duplication
(frameshift variant)
Neurodevelopmental disorder with facial dysmorphism, absent language, and pseudo-pelger-huet anomaly
GPathogenic
TMEM147
(M134R +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TMEM147
Single nucleotide variant
(intron variant)
TMEM147-related disorder
GLikely benign
TMEM147
(A126T +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TMEM147
(R127* +2 more)
Single nucleotide variant
(nonsense)
not provided
+1 more
GUncertain significance
TMEM147
(S162N +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TMEM147
(A144T +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
TMEM147
(V146I +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
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