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Items: 90

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
SKI
(P352L)
Single nucleotide variant
(missense variant)
Shprintzen-Goldberg syndrome
GUncertain significance
SRRM1
(P382L +5 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
SH3D21
(P352L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
MFSD14A
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
IBA57
(P159L +1 more)
Single nucleotide variant
(missense variant)
Hereditary spastic paraplegia 74
+1 more
GUncertain significance
SPAST
(P351L +3 more)
Single nucleotide variant
(missense variant)
Hereditary spastic paraplegia 4
GPathogenic
ARID5A
(P134L +4 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
PKP4
(P10L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
COBLL1
(P299L +4 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CHRNA1
(P377L +1 more)
Single nucleotide variant
(missense variant)
Lethal multiple pterygium syndrome
GUncertain significance
WDR12
(P214L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TTLL4
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
COL4A4
(P352L)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GConflicting classifications of pathogenicity
IL17RC
(P350L +4 more)
Single nucleotide variant
(missense variant +2 more)
Candidiasis, familial, 9
GUncertain significance
MAP4
(P243L +17 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
AMT
(P352L +2 more)
Single nucleotide variant
(missense variant +2 more)
Non-ketotic hyperglycinemia
GUncertain significance
NRROS
(P352L)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
SH3BP2
(P323L +2 more)
Single nucleotide variant
(missense variant)
Fibrous dysplasia of jaw
GUncertain significance
SLAIN2
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
PAICS
(P713L +4 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ICE1
(P352L)
Single nucleotide variant
(missense variant)
not specified
GLikely benign
ADGRV1
(P352L)
Single nucleotide variant
(missense variant +1 more)
Usher syndrome
+2 more
GPathogenic/Likely pathogenic
CTNNA1
(P24L +6 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
HARS2
(P282L +4 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GUncertain significance
DOCK2
(P352L)
Single nucleotide variant
(missense variant +1 more)
DOCK2 deficiency
GUncertain significance
RIPK1
(P515L +2 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
RREB1
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
RIMS1
(P878L +4 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
COL10A1, NT5DC1
(P352L)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+2 more
GUncertain significance
TRDN
(P352L +1 more)
Single nucleotide variant
(missense variant)
Cardiovascular phenotype
+2 more
GUncertain significance
MAP7
(P162L +16 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
PMS2
(P213L +7 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+2 more
GUncertain significance
SUGCT
(P352L +3 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ABCB4
(P352L)
Single nucleotide variant
(missense variant)
Cholestasis, intrahepatic, of pregnancy, 3
+3 more
GUncertain significance
TRPV6
(P352L)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
GUncertain significance
KCNH2
(P352L +4 more)
Single nucleotide variant
(missense variant +1 more)
Long QT syndrome
GUncertain significance
LOC129999646, WDR86
(L179F +2 more)
Single nucleotide variant
(synonymous variant +1 more)
not specified
GUncertain significance
DPYSL2
(P352L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TOP1MT
(P254L +1 more)
Single nucleotide variant
(missense variant)
not specified
+1 more
GUncertain significance
SECISBP2
(P387L +6 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
GUncertain significance
ENG
(P170L +1 more)
Single nucleotide variant
(missense variant)
Hereditary hemorrhagic telangiectasia
GLikely benign
RALGDS
(P352L +4 more)
Single nucleotide variant
(missense variant)
Hereditary breast ovarian cancer syndrome
GUncertain significance
AGAP4
(P283L +3 more)
Single nucleotide variant
(non-coding transcript variant +2 more)
not specified
GUncertain significance
GPRIN2
(P376L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
PCDH15
(P374L +3 more)
Single nucleotide variant
(missense variant)
not specified
+1 more
GUncertain significance
PSAP
(P353L +2 more)
Single nucleotide variant
(missense variant)
not provided
+2 more
GUncertain significance
ANXA7
(P312L +3 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
MMS19
(P395L +4 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
PLEKHS1
(P270L +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
PLEKHA1
(P400L +3 more)
Single nucleotide variant
(missense variant +2 more)
not specified
GUncertain significance
ADAM8
(P391L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SMPD1
(P353L +2 more)
Single nucleotide variant
(missense variant +1 more)
Inborn genetic diseases
+3 more
GConflicting classifications of pathogenicity
CARNS1, LOC130006195
(P382L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
ABCG4
(P291L +1 more)
Single nucleotide variant
(missense variant)
not provided
GBenign
LTBR
(P352L +10 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
USP5
(P348L +3 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
NEDD1
(P256L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
TMPO
(P352L)
Single nucleotide variant
(missense variant +1 more)
not specified
+1 more
GUncertain significance
TBX5
(P352L +1 more)
Single nucleotide variant
(missense variant)
Cardiovascular phenotype
GUncertain significance
ITGBL1
(P401L +3 more)
Single nucleotide variant
(missense variant)
not provided
GBenign
COL4A1
(P352L)
Single nucleotide variant
(missense variant)
Brain small vessel disease 1 with or without ocular anomalies
+2 more
GConflicting classifications of pathogenicity
TGM1
(P352L)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
FBLN5
(P279L +3 more)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
LOC126862098, NUTM1
(P352L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SHF
(P103L +4 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
CLCN7
(P352L +1 more)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
C16orf92, TLCD3B
(P266L +2 more)
Single nucleotide variant
(missense variant +1 more)
not specified
GUncertain significance
FOXC2
(P352L)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
RTN4RL1
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SLFN12L
(P352L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
G6PC1
(P352L)
Single nucleotide variant
(missense variant +1 more)
Glycogen storage disease due to glucose-6-phosphatase deficiency type IA
+1 more
GUncertain significance
BRCA1
(P1544L +75 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+4 more
GConflicting classifications of pathogenicity
BRCA1
(P1523L +75 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GUncertain significance
BRCA1
(P398L +75 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary breast ovarian cancer syndrome
+1 more
GUncertain significance
KANSL1
(P352L +2 more)
Single nucleotide variant
(missense variant)
Koolen-de Vries syndrome
GUncertain significance
GNAL, MPPE1
(P289L +2 more)
Single nucleotide variant
(3 prime UTR variant +2 more)
not specified
GUncertain significance
PRKCSH
(P352L +1 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+1 more
GConflicting classifications of pathogenicity
FCHO1
(P315L +4 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
MED25
(P352L)
Single nucleotide variant
(missense variant)
Charcot-Marie-Tooth disease type 2
GUncertain significance
DNAAF3, DNAAF3-AS1
(P419L +3 more)
Single nucleotide variant
(missense variant)
Primary ciliary dyskinesia
GUncertain significance
MYLK2
(P352L)
Single nucleotide variant
(missense variant)
Hypertrophic cardiomyopathy 1
+1 more
GUncertain significance
CDH4
(P352L +2 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
CHRNA4
(P528L +1 more)
Single nucleotide variant
(missense variant +1 more)
Autosomal dominant nocturnal frontal lobe epilepsy
+1 more
GUncertain significance
TBX1
(P352L +1 more)
Single nucleotide variant
(missense variant +1 more)
DiGeorge syndrome
+1 more
GUncertain significance
TXNRD2
(P256L +3 more)
Single nucleotide variant
(missense variant +1 more)
not provided
GUncertain significance
CHADL
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
HDAC10
(P332L +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
SBF1
(P352L +1 more)
Single nucleotide variant
(missense variant)
not provided
+1 more
GUncertain significance
NHSL2
(P352L)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
BCORL1
(P352L)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
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