C3266076[trait identifier] AND "Lupski Lab, Baylor-Hopkins CMG, Baylor - ClinVar

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 225147	NM_002336.3(LRP6):c.4593del (p.Cys1532fs)	LRP6 (C1532fs)	Deletion (frameshift variant)	Orofacial cleft +1 more	GPathogenic
Select item 225160	NM_002336.3(LRP6):c.4298C>T (p.Ser1433Leu)	LRP6 (S1433L)	Single nucleotide variant (missense variant)	Orofacial cleft +1 more	GUncertain significance
Select item 225159	NM_002336.3(LRP6):c.4136G>A (p.Gly1379Asp)	LRP6 (G1379D)	Single nucleotide variant (missense variant)	Orofacial cleft +1 more	GUncertain significance
Select item 225158	NM_002336.3(LRP6):c.3365A>C (p.Asp1122Ala)	LRP6 (D1122A)	Single nucleotide variant (missense variant)	Orofacial cleft	GUncertain significance
Select item 225157	NM_002336.3(LRP6):c.2995G>C (p.Gly999Arg)	LRP6 (G999R)	Single nucleotide variant (missense variant)	Orofacial cleft	GUncertain significance
Select item 225156	NM_002336.3(LRP6):c.2058C>G (p.Ile686Met)	LRP6 (I686M)	Single nucleotide variant (missense variant)	Orofacial cleft	GUncertain significance
Select item 225155	NM_002336.3(LRP6):c.1620G>T (p.Leu540Phe)	LRP6 (L540F)	Single nucleotide variant (missense variant)	Orofacial cleft	GUncertain significance
Select item 225154	NM_002336.3(LRP6):c.1004G>T (p.Arg335Leu)	LRP6 (R335L)	Single nucleotide variant (missense variant)	Orofacial cleft	GUncertain significance

ClinVar