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Items: 1 to 100 of 167

  • The following terms were not found in ClinVar: Bromonon, yne.
Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
P3H1
Single nucleotide variant
(splice donor variant)
Osteogenesis imperfecta type 8
+2 more
GPathogenic
ATP1A2
(P979L)
Single nucleotide variant
(missense variant)
not provided
+2 more
GPathogenic
ASPM
(K2595fs)
Deletion
(frameshift variant +1 more)
Inborn genetic diseases
+3 more
GPathogenic
CACNA1S
(Q1865fs)
Deletion
(frameshift variant)
not provided
+2 more
GUncertain significance
CACNA1S
(R1702*)
Single nucleotide variant
(nonsense)
not specified
+3 more
GConflicting classifications of pathogenicity
CACNA1S
(L1656fs)
Deletion
(frameshift variant)
Congenital myopathy 18
+3 more
GPathogenic
CACNA1S
(N1624fs)
Deletion
(frameshift variant)
Hypokalemic periodic paralysis, type 1
+1 more
GPathogenic
CACNA1S
(A1587D)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
+1 more
GConflicting classifications of pathogenicity
CACNA1S
(R1539H)
Single nucleotide variant
(missense variant)
Hypokalemic periodic paralysis, type 1
+1 more
GConflicting classifications of pathogenicity
CACNA1S
Single nucleotide variant
(synonymous variant)
Hypokalemic periodic paralysis, type 1
+4 more
GConflicting classifications of pathogenicity
CACNA1S
(V1422M)
Single nucleotide variant
(missense variant)
not provided
+3 more
GConflicting classifications of pathogenicity
CACNA1S
(S993R)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+4 more
GUncertain significance
CACNA1S
(E965Q)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
GUncertain significance
CACNA1S
(V932M)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
+2 more
GConflicting classifications of pathogenicity
CACNA1S
(N909S)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
+3 more
GConflicting classifications of pathogenicity
CACNA1S
(R794C)
Single nucleotide variant
(missense variant)
Hypokalemic periodic paralysis, type 1
+3 more
GConflicting classifications of pathogenicity
CACNA1S
(A776D)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
+1 more
GUncertain significance
CACNA1S
(R528H)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic
CACNA1S
Single nucleotide variant
(splice acceptor variant)
Hypokalemic periodic paralysis, type 1
+1 more
GLikely pathogenic
CACNA1S
(S397fs)
Microsatellite
(frameshift variant)
Malignant hyperthermia, susceptibility to, 5
+2 more
GPathogenic
CACNA1S
(D394N)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
+2 more
GConflicting classifications of pathogenicity
CACNA1S
(G384E)
Single nucleotide variant
(missense variant)
Hypokalemic periodic paralysis, type 1
+4 more
GUncertain significance
CACNA1S
(V161A)
Single nucleotide variant
(missense variant)
not provided
+3 more
GConflicting classifications of pathogenicity
CACNA1S
(R26fs)
Deletion
(frameshift variant)
Malignant hyperthermia, susceptibility to, 5
+1 more
GPathogenic
CACNA1S
(E9A)
Single nucleotide variant
(missense variant)
Malignant hyperthermia, susceptibility to, 5
GUncertain significance
MTR
(P1173L +2 more)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GPathogenic
MSH6
(K301fs +1 more)
Duplication
(frameshift variant +1 more)
Hereditary cancer-predisposing syndrome
+4 more
GPathogenic
MSH6
(I1011fs +2 more)
Duplication
(frameshift variant)
Hereditary cancer-predisposing syndrome
+5 more
GPathogenic
DCTN1
(V476L +6 more)
Single nucleotide variant
(missense variant +1 more)
Amyotrophic lateral sclerosis type 1
+4 more
GUncertain significance
LOC102724058, SCN1A
(G1869E +5 more)
Single nucleotide variant
(missense variant +1 more)
Early infantile epileptic encephalopathy with suppression bursts
+5 more
GConflicting classifications of pathogenicity
LOC102724058, SCN1A
(A1772T +5 more)
Single nucleotide variant
(missense variant +1 more)
Generalized epilepsy with febrile seizures plus, type 2
+5 more
GPathogenic
LOC102724058, SCN1A
(R1202* +5 more)
Single nucleotide variant
(nonsense +1 more)
Seizure
+4 more
GPathogenic
SCN1A
(I448T)
Single nucleotide variant
(missense variant +2 more)
Developmental and epileptic encephalopathy 6B
+5 more
GUncertain significance
SCN1A
(T398M)
Single nucleotide variant
(missense variant +2 more)
not provided
+4 more
GConflicting classifications of pathogenicity
SCN1A
(T226M)
Single nucleotide variant
(missense variant +2 more)
Migraine, familial hemiplegic, 3
+6 more
GPathogenic
SCN1A
(R222*)
Single nucleotide variant
(nonsense +2 more)
Severe myoclonic epilepsy in infancy
+6 more
GPathogenic/Likely pathogenic
SCN1A
Single nucleotide variant
(splice donor variant)
Early infantile epileptic encephalopathy with suppression bursts
+7 more
GPathogenic
TTN-AS1, TTN
(R29904H +5 more)
Single nucleotide variant
(missense variant)
not specified
+7 more
GUncertain significance
COL3A1
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+2 more
GPathogenic
CRTAP
Single nucleotide variant
(splice donor variant)
Osteogenesis imperfecta type 7
+2 more
GPathogenic/Likely pathogenic
F12, SLC34A1
(T328K)
Single nucleotide variant
(missense variant)
Hereditary angioneurotic edema
+3 more
GPathogenic
SQSTM1
(P392L +1 more)
Single nucleotide variant
(missense variant)
Paget disease of bone 3
+6 more
GConflicting classifications of pathogenicity
HFE, HFE-AS1
(H63D +1 more)
Single nucleotide variant
(non-coding transcript variant +2 more)
Cardiomyopathy
+9 more
GPathogenic/Likely pathogenic/Pathogenic, low penetrance; other
HFE
(C282Y +8 more)
Single nucleotide variant
(missense variant +1 more)
Juvenile hemochromatosis
+19 more
GPathogenic/Pathogenic, low penetrance; other; risk factor
PMS2
Deletion
(nonsense +1 more)
not provided
+5 more
GPathogenic
GCK
(S263P +2 more)
Single nucleotide variant
(missense variant)
Maturity-onset diabetes of the young type 2
+3 more
GPathogenic/Likely pathogenic
IKZF1
Single nucleotide variant
(intron variant)
Leukemia, acute lymphocytic, susceptibility to, 2
Gassociation
CFTR, CFTR-AS1
(D443Y)
Single nucleotide variant
(missense variant)
Cystic fibrosis
+6 more
GConflicting classifications of pathogenicity
TSC1
(Q897* +3 more)
Single nucleotide variant
(nonsense)
Tuberous sclerosis 1
+2 more
GPathogenic
TSC1
(K587R +3 more)
Single nucleotide variant
(missense variant)
not provided
+4 more
GBenign
TSC1
(D317fs +2 more)
Deletion
(frameshift variant)
Tuberous sclerosis syndrome
GPathogenic
TSC1
Deletion
(nonsense)
Tuberous sclerosis syndrome
+2 more
GPathogenic
NOTCH1
(A2069T)
Single nucleotide variant
(missense variant)
Marfan syndrome
+5 more
GConflicting classifications of pathogenicity
TMEM38B
Deletion
Osteogenesis imperfecta
GLikely pathogenic
REXO4, RNU6ATAC
+100 more
Duplication
Tuberous sclerosis 1
+4 more
GUncertain significance
IFITM5, PGGHG
Single nucleotide variant
(5 prime UTR variant)
Postmenopausal osteoporosis
+3 more
GPathogenic
MYBPC3
Deletion
Hypertrophic cardiomyopathy
+6 more
GPathogenic/Likely pathogenic
MYBPC3
(Y237H)
Single nucleotide variant
(missense variant)
MYBPC3-related disorder
+5 more
GConflicting classifications of pathogenicity
MYBPC3
(G5R)
Single nucleotide variant
(missense variant)
Hypertrophic cardiomyopathy
+5 more
GConflicting classifications of pathogenicity
SERPING1
(N272del)
Microsatellite
(inframe_deletion)
Hereditary angioedema type 1
+1 more
GConflicting classifications of pathogenicity
PTPN11
(E139D +1 more)
Single nucleotide variant
(missense variant)
Noonan syndrome
GPathogenic
PTPN11
(Q510P +2 more)
Single nucleotide variant
(missense variant)
Noonan syndrome with multiple lentigines
GPathogenic
TRIP11
Single nucleotide variant
(splice donor variant)
Achondrogenesis, type IA
+2 more
GUncertain significance
SERPINA1
(P393S)
Single nucleotide variant
(missense variant)
not provided
+1 more
GConflicting classifications of pathogenicity
SERPINA1
(E366K)
Single nucleotide variant
(missense variant)
Neurodevelopmental disorder
+6 more
GPathogenic; risk factor
SERPINA1
(E288V)
Single nucleotide variant
(missense variant)
Chronic obstructive pulmonary disease
+3 more
GPathogenic/Pathogenic, low penetrance; other
FBN1
(E2610K)
Single nucleotide variant
(missense variant)
Ectopia lentis 1, isolated, autosomal dominant
+9 more
GPathogenic/Likely pathogenic
FBN1
(R2576C)
Single nucleotide variant
(missense variant)
Marfan syndrome
GPathogenic
FBN1
(E2570K)
Single nucleotide variant
(missense variant)
not provided
+3 more
GPathogenic/Likely pathogenic
FBN1
(G2514R)
Single nucleotide variant
(missense variant)
Marfan syndrome
GPathogenic
FBN1
(K2460R)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+3 more
GUncertain significance
FBN1
Single nucleotide variant
(intron variant)
Marfan syndrome
+4 more
GPathogenic/Likely pathogenic
FBN1
(G1762S)
Single nucleotide variant
(missense variant)
Geleophysic dysplasia 2
+3 more
GPathogenic
FBN1
(R1170H)
Single nucleotide variant
(missense variant)
Marfan syndrome
GBenign
FBN1
(R974C)
Single nucleotide variant
(missense variant)
Marfan syndrome
+3 more
GPathogenic/Likely pathogenic
FBN1
(C908R)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+2 more
GPathogenic/Likely pathogenic
FBN1
(A882V)
Single nucleotide variant
(missense variant)
Marfan syndrome
+11 more
GPathogenic/Likely pathogenic
FBN1
(R861*)
Single nucleotide variant
(nonsense)
Isolated thoracic aortic aneurysm
+12 more
GPathogenic/Likely pathogenic
FBN1
(I849M)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+3 more
GConflicting classifications of pathogenicity
FBN1
(R627C)
Single nucleotide variant
(missense variant)
Acromicric dysplasia
+10 more
GPathogenic
FBN1
(R565*)
Single nucleotide variant
(nonsense)
Marfan syndrome
+3 more
GPathogenic
FBN1, LOC113939944
(R364*)
Single nucleotide variant
(nonsense)
Marfan syndrome
+5 more
GPathogenic/Likely pathogenic
FBN1
(C168Y)
Single nucleotide variant
(missense variant)
Familial thoracic aortic aneurysm and aortic dissection
+2 more
GPathogenic/Likely pathogenic
FBN1
Single nucleotide variant
(intron variant)
Weill-Marchesani syndrome
+7 more
GConflicting classifications of pathogenicity
FBN1
(R62C)
Single nucleotide variant
(missense variant)
Familial ectopia lentis
+10 more
GPathogenic
PPIB, SNX22
(K186fs)
Deletion
(frameshift variant +2 more)
Osteogenesis imperfecta
+1 more
GPathogenic
BLM
(Q548* +1 more)
Single nucleotide variant
(nonsense)
not provided
+2 more
GPathogenic
TSC2
(L91fs +4 more)
Duplication
(frameshift variant)
Tuberous sclerosis syndrome
GPathogenic
TSC2
(L733V +4 more)
Single nucleotide variant
(missense variant)
Tuberous sclerosis 2
GPathogenic/Likely pathogenic
TSC2
Deletion
(inframe_deletion)
not provided
+3 more
GPathogenic/Likely pathogenic
MEFV
(V726A)
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever
+5 more
GPathogenic/Likely pathogenic
LOC126862264, MEFV
(K695R)
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever, autosomal dominant
+9 more
GConflicting classifications of pathogenicity
LOC126862264, MEFV
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever, autosomal dominant
+24 more
GPathogenic/Likely pathogenic
LOC126862264, MEFV
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever, autosomal dominant
+3 more
GPathogenic
LOC126862264, MEFV
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever
+6 more
GConflicting classifications of pathogenicity
MEFV
(P158S)
Single nucleotide variant
(missense variant)
not specified
+4 more
GConflicting classifications of pathogenicity
MEFV
(R329H +1 more)
Single nucleotide variant
(missense variant)
not specified
+13 more
GConflicting classifications of pathogenicity
MEFV
(G304R)
Single nucleotide variant
(missense variant +1 more)
not specified
+3 more
GConflicting classifications of pathogenicity
MEFV
(T267I)
Single nucleotide variant
(missense variant +1 more)
Familial Mediterranean fever, autosomal dominant
+4 more
GConflicting classifications of pathogenicity
MEFV
(G196W)
Single nucleotide variant
(missense variant +1 more)
not specified
+4 more
GConflicting classifications of pathogenicity
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