U.S. flag

An official website of the United States government

Format
Items per page
Sort by
Choose Destination

Links from Orgtrack

Items: 54

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
DEPDC5
Copy number gain
Epilepsy, familial focal, with variable foci 1
GLikely pathogenic
SLC3A1
(S168*)
Single nucleotide variant
(nonsense)
Cystinuria
GLikely pathogenic
FANCA
Deletion
(splice acceptor variant)
Fanconi anemia complementation group A
GPathogenic
EHMT1
(C902R +1 more)
Single nucleotide variant
(missense variant)
Kleefstra syndrome 1
GPathogenic
GLI3
(P1482fs)
Deletion
(frameshift variant)
Greig cephalopolysyndactyly syndrome
GLikely pathogenic
MTM1
(F270fs +1 more)
Deletion
(frameshift variant)
Severe X-linked myotubular myopathy
GLikely pathogenic
LMNA
(A331V +5 more)
Indel
(missense variant +1 more)
Emery-Dreifuss muscular dystrophy 2, autosomal dominant
GUncertain significance
ANKRD11
(S983fs)
Microsatellite
(frameshift variant)
KBG syndrome
GPathogenic
KAT6A
(E1297fs)
Duplication
(frameshift variant)
Autosomal dominant intellectual disability-craniofacial anomalies-cardiac defects syndrome
GLikely pathogenic
COL4A4
(G663S)
Single nucleotide variant
(missense variant)
Autosomal recessive Alport syndrome
GPathogenic
DYRK1A
(K369fs +2 more)
Duplication
(frameshift variant)
DYRK1A-related intellectual disability syndrome
GPathogenic
GNB1
(W99L)
Single nucleotide variant
(5 prime UTR variant +1 more)
Intellectual disability, autosomal dominant 42
GLikely pathogenic
CRTAP
(A268fs +2 more)
Deletion
(frameshift variant)
Osteogenesis imperfecta type 7
GLikely pathogenic
EPHB4
(Y175*)
Single nucleotide variant
(nonsense)
Capillary malformation-arteriovenous malformation 2
GLikely pathogenic
TSC2
(V1476fs +34 more)
Deletion
(frameshift variant +1 more)
Tuberous sclerosis 2
GLikely pathogenic
HADHB
(A370del +2 more)
Deletion
(inframe_deletion)
Mitochondrial trifunctional protein deficiency 2
GLikely pathogenic
BRCA2
(P1152fs +3 more)
Deletion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely pathogenic
BRCA2
(T1412fs)
Indel
(frameshift variant +2 more)
Pancreatic cancer, susceptibility to, 2
GLikely pathogenic
BRCA2
(N466fs)
Duplication
(frameshift variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely pathogenic
BRCA2
(E456fs)
Deletion
(frameshift variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 2
GLikely pathogenic
BRCA1
(R152fs +20 more)
Deletion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely pathogenic
SERPING1
(P399R)
Single nucleotide variant
(missense variant)
Hereditary angioedema type 1
GPathogenic
KCNC1
(S341R)
Single nucleotide variant
(missense variant)
Progressive myoclonic epilepsy type 7
GLikely pathogenic
COL7A1
(G2542R)
Single nucleotide variant
(missense variant)
Recessive dystrophic epidermolysis bullosa
GLikely pathogenic
GJB1
(I137fs)
Duplication
(frameshift variant)
Charcot-Marie-Tooth disease X-linked dominant 1
GLikely pathogenic
KMT5B
(R543* +2 more)
Single nucleotide variant
(nonsense)
Intellectual disability, autosomal dominant 51
GLikely pathogenic
MYT1L
(C509Y +1 more)
Single nucleotide variant
(missense variant)
Intellectual disability, autosomal dominant 39
GLikely pathogenic
CACNA1G
(M1506I +2 more)
Single nucleotide variant
(missense variant +3 more)
Spinocerebellar ataxia type 42
GLikely pathogenic
TAPBPL, VAMP1
(N51fs)
Duplication
(frameshift variant +1 more)
Spastic ataxia 1
GLikely pathogenic
DCX
(A315V +6 more)
Single nucleotide variant
(missense variant)
Lissencephaly type 1 due to doublecortin gene mutation
GLikely pathogenic
ATL1
(N440T)
Single nucleotide variant
(missense variant)
Hereditary spastic paraplegia 3A
GPathogenic
CNKSR2
(R650* +3 more)
Single nucleotide variant
(nonsense)
Intellectual disability, X-linked, syndromic, Houge type
GLikely pathogenic
FLNB
Deletion
(nonsense)
Spondylocarpotarsal synostosis syndrome
GLikely pathogenic
COL4A1
Deletion
(splice acceptor variant +1 more)
Brain small vessel disease 1 with or without ocular anomalies
GPathogenic
CHRNG
(R86H)
Single nucleotide variant
(missense variant)
Autosomal recessive multiple pterygium syndrome
+1 more
GConflicting classifications of pathogenicity
TCF12
Single nucleotide variant
(intron variant)
TCF12-related craniosynostosis
+1 more
GConflicting classifications of pathogenicity
NAGLU
(N435T)
Single nucleotide variant
(missense variant)
Mucopolysaccharidosis, MPS-III-B
+1 more
GConflicting classifications of pathogenicity
DYM
(K19fs)
Insertion
(frameshift variant)
Dyggve-Melchior-Clausen syndrome
GLikely pathogenic
GNAS
Deletion
(inframe_deletion +1 more)
Pseudohypoparathyroidism type 1C
+1 more
GLikely pathogenic
COL4A5
(G224V)
Single nucleotide variant
(missense variant)
X-linked Alport syndrome
GLikely pathogenic
PKD1
(G168fs)
Deletion
(frameshift variant)
Polycystic kidney disease, adult type
GPathogenic
GNB1
(C166R +1 more)
Single nucleotide variant
(missense variant)
Intellectual disability, autosomal dominant 42
GLikely pathogenic
RYR1
(I4932V +1 more)
Single nucleotide variant
(missense variant)
not specified
GUncertain significance
WFS1
(S826N)
Single nucleotide variant
(missense variant)
Wolfram syndrome 1
GLikely risk allele
TSC1
(R321* +3 more)
Single nucleotide variant
(nonsense)
Tuberous sclerosis 1
GLikely pathogenic
SPTAN1
(L1527Q +2 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 5
GLikely pathogenic
NHLRC1
(P85R)
Single nucleotide variant
(missense variant)
Myoclonic epilepsy of Lafora 2
GUncertain significance
DDX3X
Deletion
(intron variant)
Intellectual disability, X-linked 102
GLikely pathogenic
KCNQ3
(A35fs)
Deletion
(frameshift variant)
Seizures, benign familial neonatal, 2
GLikely pathogenic
OPA1
(L55fs)
Duplication
(5 prime UTR variant +1 more)
Autosomal dominant optic atrophy classic form
GLikely pathogenic
ATM, C11orf65
+2 more
Duplication
Ataxia-telangiectasia syndrome
GPathogenic
SERPING1
(V206fs)
Duplication
(frameshift variant)
Hereditary angioedema type 1
GPathogenic
ATM, C11orf65
(W2300S)
Single nucleotide variant
(missense variant +1 more)
Ataxia-telangiectasia syndrome
GConflicting classifications of pathogenicity
COL7A1
(R2791W)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GConflicting classifications of pathogenicity
Format
Items per page
Sort by
Choose Destination